3 Results for "

Erythrina suberosa

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Erythrina suberosa" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N1073
CAS No.: 51225-30-0
Synonyms: 6-Isopentenylgenistein; Erythrinin B
Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR L858R/T790M mutation, and fungal infections .
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1
1 Cited Publications
Cat. No.: HY-N3857
CAS No.: 63807-85-2
Erythrinin C is an isoflavones that can be isolated from Erythrina suberosa var .
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Cat. No.: HY-N3642
CAS No.: 74515-47-2
Synonyms: Erythrabyssin I; Erythrabissin I
Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence .
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