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Results for "

Fusarium species

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Reactive Oxygen Species (ROS) (1) Acyltransferase (2) Apoptosis (1) Bacterial (2) Ceramidase (1) Estrogen Receptor/ERR (2) Fungal (3) Isotope-Labeled Compounds (3) Mitochondrial Metabolism (1) Myosin (2) Reference Standards (3)
By Research Areas:	Cancer (3) Endocrinology (5) Infection (8) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Reactive Oxygen Species (ROS)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6723

Fumonisin B2	Ceramidase Acyltransferase	Infection Cancer
Fumonisin B2 is a selective ceramide synthase inhibitor and carcinogenic mycotoxin with toxicity comparable to that of Fumonisin B1 (HY-N6719). Fumonisin B2 inhibits de novo sphingolipid biosynthesis by blocking the amide bond formation between fatty acids and dihydrosphingosine, which leads to a massive intracellular accumulation of free dihydrosphingosine, altered sphingosine levels, subsequent inhibition of cell proliferation, and induction of cell death. Fumonisin B2 is used to investigate the pathogenesis of diseases associated with Fusarium verticillioides contamination, including equine leukoencephalomalacia, porcine pulmonary edema syndrome, human esophageal cancer, and rat hepatocellular carcinoma .

HY-N6741

β-Zearalenol	Others	Infection Endocrinology
β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level .

HY-130307

Rubrofusarin	Bacterial	Neurological Disease Inflammation/Immunology Cancer
Rubrofusarin is an orange polyketide pigment from Fusarium graminearum . Rubrofusarin is also an active ingredient of the Cassia species and ameliorates chronic restraint stress (CRS) -induced depressive symptoms through PI3K/Akt signaling. Rubrofusarin has anticancer, antibacterial, and antioxidant effects .

HY-N6706

Enniatin complex	Bacterial Acyltransferase Apoptosis	Infection Cancer
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines .

HY-122200R

Phenamacril (Standard) JS399-19 (Standard)	Reference Standards Myosin Fungal	Infection
Phenamacril (Standard) is the analytical standard of Phenamacril. This product is intended for research and analytical applications. Phenamacril (JS399-19) inhibits activity of myosin I non-competitively with an IC50 of 360 nM through suppression of the ATPase activity, exhibits therefore an antifungal efficacy towards Fusarium species .

HY-N12982

α-Calacorene	Others	Others
α-Calacorene is a sesquiterpene that can be isolated from Réunion vetiver oil .

HY-122200

Phenamacril JS399-19	Myosin Fungal	Infection
Phenamacril (JS399-19) inhibits activity of myosin I non-competitively with an IC₅₀ of 360 nM through suppression of the ATPase activity, exhibits therefore an antifungal efficacy towards Fusarium species .

HY-122785

Fusapyrone	Fungal	Infection
Fusapyrone is a broad-spectrum antifungal metabolite first isolated from Fusarium species. It has been investigated for use in the control of postharvest crop diseases such as inhibiting the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes.

HY-N6678S

(Rac)-Zearalanone-d6	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology
(Rac)-Zearalanone-d₆ is the racemate of Zearalanone. Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

HY-N6678R

Zearalanone (Standard)	Reference Standards Estrogen Receptor/ERR	Endocrinology
Zearalanone (Standard) is the analytical standard of Zearalanone. This product is intended for research and analytical applications. Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

HY-N6741R

β-Zearalenol (Standard)	Reference Standards Others	Infection Endocrinology
β-Zearalenol (Standard) is the analytical standard of β-Zearalenol. This product is intended for research and analytical applications. β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level .

HY-W402074

5-Acetamide-Butenolide Butenolide	Mitochondrial Metabolism Reactive Oxygen Species (ROS)	Metabolic Disease
5-Acetamide-Butenolide (Butenolide) is a mycotoxin with pro-oxidant activity, which is found in Fusarium. 5-Acetamide-Butenolide disrupts the mitochondrial membrane potential in primary neonatal rat cardiomyocytes. 5-Acetamide-Butenolide also induces the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. 5-Acetamide-Butenolide increases the production of reactive oxygen species (ROS), decreases the levels of GSH and reduces the viability of HepG2 cells .

HY-N6678S1

Zearalanone-13C18	Isotope-Labeled Compounds	Endocrinology
Zearalanone- ¹³C₁₈ is the ¹³C-labeled Zearalanone (HY-N6678). Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

HY-N6741S

β-Zearalenol-13C18	Isotope-Labeled Compounds	Infection
β-Zearalenol- ¹³C₁₈ is the ¹³C-labeled β-Zearalenol. β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6723

Fumonisin B2	Infection Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Endogenous metabolite Disease Research Fields Other Antibiotics Source Classification	Ceramidase Acyltransferase
Fumonisin B2 is a selective ceramide synthase inhibitor and carcinogenic mycotoxin with toxicity comparable to that of Fumonisin B1 (HY-N6719). Fumonisin B2 inhibits de novo sphingolipid biosynthesis by blocking the amide bond formation between fatty acids and dihydrosphingosine, which leads to a massive intracellular accumulation of free dihydrosphingosine, altered sphingosine levels, subsequent inhibition of cell proliferation, and induction of cell death. Fumonisin B2 is used to investigate the pathogenesis of diseases associated with Fusarium verticillioides contamination, including equine leukoencephalomalacia, porcine pulmonary edema syndrome, human esophageal cancer, and rat hepatocellular carcinoma .

HY-N6741

β-Zearalenol	Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Phenols Polyphenols Antibacterial Disease Research Disease Research Fields Endocrinology Source Classification	Others
β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level .

HY-130307

Rubrofusarin	Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
Rubrofusarin is an orange polyketide pigment from Fusarium graminearum . Rubrofusarin is also an active ingredient of the Cassia species and ameliorates chronic restraint stress (CRS) -induced depressive symptoms through PI3K/Akt signaling. Rubrofusarin has anticancer, antibacterial, and antioxidant effects .

HY-N6706

Enniatin complex	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification	Bacterial Acyltransferase Apoptosis
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines .

HY-N12982

α-Calacorene	Structural Classification Terpenoids Gramineae Sesquiterpenes Plants Chrysopogon zizanioides (L.) Roberty Source Classification	Others
α-Calacorene is a sesquiterpene that can be isolated from Réunion vetiver oil .

HY-N6678R

Zearalanone (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Phenols Polyphenols Antibacterial Disease Research Anticancer Source Classification	Reference Standards Estrogen Receptor/ERR
Zearalanone (Standard) is the analytical standard of Zearalanone. This product is intended for research and analytical applications. Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

HY-N6741R

β-Zearalenol (Standard)	Microorganisms Classification of Application Fields Antibiotics Phenols Disease Research Fields Endocrinology Source Classification	Reference Standards Others
β-Zearalenol (Standard) is the analytical standard of β-Zearalenol. This product is intended for research and analytical applications. β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level .

HY-W402074

5-Acetamide-Butenolide Butenolide	Structural Classification Alkaloids Other Alkaloids Poaceae Plants Festuca arundinacea Schreb. Source Classification	Mitochondrial Metabolism Reactive Oxygen Species (ROS)
5-Acetamide-Butenolide (Butenolide) is a mycotoxin with pro-oxidant activity, which is found in Fusarium. 5-Acetamide-Butenolide disrupts the mitochondrial membrane potential in primary neonatal rat cardiomyocytes. 5-Acetamide-Butenolide also induces the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. 5-Acetamide-Butenolide increases the production of reactive oxygen species (ROS), decreases the levels of GSH and reduces the viability of HepG2 cells .

Cat. No.	Product Name	Chemical Structure

HY-N6678S

(Rac)-Zearalanone-d6
(Rac)-Zearalanone-d₆ is the racemate of Zearalanone. Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

(Rac)-Zearalanone-d6

(Rac)-Zearalanone-d₆ is the racemate of Zearalanone. Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

HY-N6678S1

Zearalanone-13C18
Zearalanone- ¹³C₁₈ is the ¹³C-labeled Zearalanone (HY-N6678). Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

Zearalanone-13C18

Zearalanone- ¹³C₁₈ is the ¹³C-labeled Zearalanone (HY-N6678). Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system .

HY-N6741S

β-Zearalenol-13C18
β-Zearalenol- ¹³C₁₈ is the ¹³C-labeled β-Zearalenol. β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level .

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