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GDP-L-fucose

" in MedChemExpress (MCE) Product Catalog:

7

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Biochemical Assay Reagents

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Recombinant Proteins

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Click Chemistry

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134433
    GDP-L-fucose

    		Endogenous Metabolite Metabolic Disease
    GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats .
    GDP-L-fucose
  • HY-134433A
    GDP-L-fucose disodium

    		Endogenous Metabolite Metabolic Disease
    GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .
    GDP-L-fucose disodium
  • HY-N7389A
    GDP-D-mannose disodium

    		Endogenous Metabolite Drug Intermediate Metabolic Disease
    GDP-D-mannose disodium consists of GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-β-L-fucose. GDP-α-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 μM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 μM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG) .
    GDP-D-mannose disodium
  • HY-164169
    GDP-azido-fucose

    		Biochemical Assay Reagents Others
    GDP-Azido-Fucose is a chemically modified donor substrate. GDP-Azido-Fucose can be used to synthesize fluorophore-conjugated GDP-fucose. GDP-Azido-Fucose can be used to study glycosyltransferase reactions .
    GDP-azido-fucose
  • HY-177787A
    2'-Deoxy-N-methyl-AMP ammonium

    		Nucleoside Antimetabolite/Analog Others
    2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .
    2'-Deoxy-N-methyl-AMP ammonium
  • HY-164169A
    GDP-azido-fucose disodium

    		Biochemical Assay Reagents Others
    GDP-Azido-Fucose disodium is a chemically modified donor substrate. GDP-Azido-Fucose disodium can be used to synthesize fluorophore-conjugated GDP-fucose. GDP-Azido-Fucose can be used to study glycosyltransferase reactions .
    GDP-azido-fucose disodium
  • HY-E71208
    α-1,2-Colitosyltransferase

    		Biochemical Assay Reagents Others
    α-1,2-Colitosyltransferase (EC 2.4.1.341) participates in the biosynthesis of an O-antigen. The reaction involves anomeric inversion, and does not require any metal ions. The enzyme is highly specific towards the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-β-L-colitose.
    α-1,2-Colitosyltransferase

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