10 Results for "

GDP-L-fucose

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "GDP-L-fucose" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-134433
CAS No.: 15839-70-0
Purity:  99.82%
GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats .
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1
1 Cited Publications
Cat. No.: HY-134433A
CAS No.: 148296-47-3
Purity:  99.78%
GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .
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Cat. No.: HY-N7389A
CAS No.: 103301-73-1
GDP-D-mannose disodium consists of GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-β-L-fucose. GDP-α-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 μM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 μM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG) .
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Cat. No.: HY-164169
CAS No.: 912921-33-6
Research Areas:  

Others

GDP-azido-fucose is a glycoengineering tool. GDP-azido-fucose modifies complex glycans by adding an azido-fucose group. GDP-azido-fucose can install azido-fucose tags on antibody Fc glycans for site-specific payload conjugation, thereby forming antibody-drug conjugates with defined ratios .
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Cat. No.: HY-177787A
Research Areas:  

Others

2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .
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Cat. No.: HY-P811090
Synonyms: SDR4E1, TSTA3, GFUS, GDP-L-fucose synthase, Protein FX, Red cell NADP(H)-binding protein, Short-chain dehydrogenase/reductase family 4E member 1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-E71208
Research Areas:  

Others

α-1,2-Colitosyltransferase (EC 2.4.1.341) participates in the biosynthesis of an O-antigen. The reaction involves anomeric inversion, and does not require any metal ions. The enzyme is highly specific towards the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-β-L-colitose.
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Cat. No.: HY-164169A
CAS No.: 944560-34-3
Research Areas:  

Others

GDP-azido-fucose disodium is a glycoengineering tool. GDP-azido-fucose disodium modifies complex glycans by adding an azido-fucose group. GDP-azido-fucose disodium can install azido-fucose tags on antibody Fc glycans for site-specific payload conjugation, thereby forming antibody-drug conjugates with defined ratios .
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Cat. No.: HY-P706175
Purity:  ≥ 90%, as determined by SDS-PAGE.
Synonyms: FUT1; Fucosyltransferase 1 (Galactoside 2-Alpha-L-Fucosyltransferase); Prev. HSC; Truncated Alpha(1,2)Fucosyltransferase; Prev. H; A-1, 2 Fucosyltransferase (H Antigen); GDP-L-fucose:Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 1; Nonfunctional Fucosyl
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-116705G
CAS No.: 70763-62-1
Synonyms: 2-Fluorofucose (GMP)
2-Deoxy-2-fluoro-L-fucose (2-Fluorofucose) GMP is a fucosyltransferase inhibitor that inhibits core fucosylation modification in cells. 2-Deoxy-2-fluoro-L-fucose GMP promotes the production of defucosylated IgG1 antibodies in IgG1-expressing cell culture systems; it regulates the levels of inflammatory cytokines such as IL-1β, IL-6 and TGF-β in human induced pluripotent stem cell-derived microglia. 2-Deoxy-2-fluoro-L-fucose GMP can be used in the research of related diseases including dengue fever and Alzheimer's disease .
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