GDP-L-fucose
Based on 1 publication(s) in Google Scholar
GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 15839-70-0
- Formula: C16H25N5O15P2
- Molecular Weight:589.34
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) GDP-L-fucose
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
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Human Endogenous Metabolite |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15839-70-0
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Appearance Solid
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Molecular Weight 589.34
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Formula C16H25N5O15P2
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Color White to off-white
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SMILES
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(O)(OP(O)(O[C@@H]4[C@@H](O)[C@H](O)[C@H](O)[C@H](C)O4)=O)=O)O3)=C2N=C(N)N1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Plant Cell
SlSEC1- and SlSPY-mediated O-glycosylation stabilizes the transcription factor SlNOR to promote tomato fruit ripening. [Abstract]2026 May 14:koag144. PMID: 42135064
Solvent & Solubility
H2O : 100 mg/mL (169.68 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Weiyang Wang, et al. Cell-free enzymatic synthesis of GDP-L-fucose from mannose. AMB Express. 2019 May 27;9(1):74. [Content Brief]
[2]. 1. Wiese TJ, et al. Effect of L-fucose and D-glucose concentration on L-fucoprotein metabolism in human Hep G2 cells and changes in fucosyltransferase and alpha-L-fucosidase activity in liver of diabetic rats. Biochim Biophys Acta. 1997 Apr 17;1335(1-2):61-72. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6968 mL | 8.4841 mL | 16.9681 mL | 42.4203 mL |
| 5 mM | 0.3394 mL | 1.6968 mL | 3.3936 mL | 8.4841 mL | |
| 10 mM | 0.1697 mL | 0.8484 mL | 1.6968 mL | 4.2420 mL | |
| 15 mM | 0.1131 mL | 0.5656 mL | 1.1312 mL | 2.8280 mL | |
| 20 mM | 0.0848 mL | 0.4242 mL | 0.8484 mL | 2.1210 mL | |
| 25 mM | 0.0679 mL | 0.3394 mL | 0.6787 mL | 1.6968 mL | |
| 30 mM | 0.0566 mL | 0.2828 mL | 0.5656 mL | 1.4140 mL | |
| 40 mM | 0.0424 mL | 0.2121 mL | 0.4242 mL | 1.0605 mL | |
| 50 mM | 0.0339 mL | 0.1697 mL | 0.3394 mL | 0.8484 mL | |
| 60 mM | 0.0283 mL | 0.1414 mL | 0.2828 mL | 0.7070 mL | |
| 80 mM | 0.0212 mL | 0.1061 mL | 0.2121 mL | 0.5303 mL | |
| 100 mM | 0.0170 mL | 0.0848 mL | 0.1697 mL | 0.4242 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.