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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
GPR81 agonist
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "GPR81 agonist" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-W016868
CAS No.: 53984-36-4
Research Areas:
3-Chloro-5-hydroxybenzoic acid is a potent, orally active and selective lactate receptor GPR81 agonist, with an EC50 of 16 μM for human GPR81. 3-Chloro-5-hydroxybenzoic acid exhibits favorable in vivo effects on lipolysis in a mouse model of obesity .
4
4 Cited Publications
Research Areas:
GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a .
1
1 Cited Publications
Cat. No.: HY-W015560
CAS No.: 99-10-5
Cat. No.: HY-W004049
CAS No.: 99-06-9
Cat. No.: HY-148563
CAS No.: 1143024-28-5
Research Areas:
GPR81 agonist 2 is a GPR81 agonist with an EC50 of 0.023 μM for the human receptor. GPR81 agonist 2 activates the lactate-sensing receptor GPR81, inhibits forskolin-stimulated cAMP production and GTP binding of Gi protein. GPR81 agonist 2 can be used for research on type 2 diabetes .
Cat. No.: HY-W004049R
CAS No.: 99-06-9
Cat. No.: HY-W015560R
CAS No.: 99-10-5
Cat. No.: HY-W004049S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
