264 Results for "

H1N1

" in MedChemExpress (MCE) Product Catalog:
Products (264)

264 Results for "H1N1" in MCE Product Catalog:

77
77 Publications Verification
Cat. No.: HY-10964
CAS No.: 117570-53-3
Purity:  99.93%
Synonyms: DMXAA; ASA-404
Research Areas:  

Infection Cancer

Vadimezan (DMXAA), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities.
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49
49 Cited Publications
Cat. No.: HY-13317
CAS No.: 196618-13-0
Purity:  99.94%
Synonyms: GS 4104
Target:  

Influenza Virus

Research Areas:  

Infection Cancer

Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively .
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11
11 Cited Publications
Cat. No.: HY-N0736
CAS No.: 6020-18-4
Coptisine chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM. Coptisine chloride is a potent H1N1 neuraminidase (NA-1) inhibitor with an IC50 of 104.6?μg/mL and can be used for influenza A (H1N1) infection.
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11
11 Cited Publications
Cat. No.: HY-107201
CAS No.: 7585-39-9
Purity:  99.95%
Synonyms: Betadex
Target:  

Influenza Virus

Research Areas:  

Infection

β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.
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11
11 Cited Publications
Cat. No.: HY-12882
CAS No.: 23210-56-2
Purity:  99.94%
Synonyms: NP-120; RC-61-91
Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) . Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
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11
11 Cited Publications
Cat. No.: HY-12882A
CAS No.: 23210-58-4
Purity:  99.95%
Synonyms: NP-120 tartrate; RC-61-91 tartrate
Ifenprodil (NP-120) tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) . Ifenprodil tartrate is an α1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
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7
7 Cited Publications
Cat. No.: HY-N0638
CAS No.: 2115-91-5
Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively. Dendrobine activates the JNK/p38/Nrf2 signaling pathway. Dendrobine exhibits antiviral, antitumor, anti-inflammatory, and neuroprotective properties .
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6
6 Cited Publications
Cat. No.: HY-N0243
CAS No.: 4670-05-7
Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
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2
2 Cited Publications
Cat. No.: HY-N0440
CAS No.: 6902-91-6
Germacrone is a sesquiterpene compound with multiple biological activities. Germacrone inhibits the H1N1 and H3N2 influenza A virus and the influenza B virus. Germacrone blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone inhibits 5α-reductase and has anti-androgenic effect. Germacrone has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone also has antioxidant activity .
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1
1 Cited Publications
Cat. No.: HY-P76447
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Influenza A H1N1 (A/California/04/2009) Hemagglutinin / HA0 Protein
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P73784
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NA; Neuraminidase; NA/Neuraminidase Protein, H1N1 (A/Sw/Bulnes/VN1401-P6SP/2018, HEK293, His)
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-19519
CAS No.: 849776-05-2
Synonyms: DF 2156A free base
Target:  

CXCR

Research Areas:  

Inflammation/Immunology Cancer

Ladarixin (DF 2156A free base) is an orally active, allosteric non-competitive and dual CXCR1 and CXCR2 antagonist. Ladarixin can be used for the research of COPD and asthma .
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1
1 Cited Publications
Cat. No.: HY-19519A
CAS No.: 865625-56-5
Synonyms: DF 2156A
Target:  

CXCR

Ladarixin sodium (DF 2156A) is an orally active, allosteric non-competitive and dual CXCR1 and CXCR2 antagonist. Ladarixin sodium can be used for the research of COPD and asthma .
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1
1 Cited Publications
Cat. No.: HY-N6025
CAS No.: 112747-98-5
Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .
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Cat. No.: HY-P99620
CAS No.: 1443004-15-6
Synonyms: CT-P22; CT120

Target:  

Influenza Virus

Research Areas:  

Infection

Firivumab (CT-P22; CT120) is a human IgG1 monoclonal influenza A virus hemagglutinin (Anti-IAV HA) antibody. Firivumab is capable of neutralizing H1N1, H5N1, H6N1, H6N2, H8N4, H8N8, H9N2 and H12N7. Firivumab shows protection against H1N1 virus in mice .
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Cat. No.: HY-126136
CAS No.: 1638211-04-7
Purity:  99.62%
Target:  

Influenza Virus

Research Areas:  

Infection

ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1 .
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Cat. No.: HY-137334
CAS No.: 2379438-80-7
Purity:  98.93%
Target:  

Influenza Virus

Research Areas:  

Infection

Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus .
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Cat. No.: HY-N0224A
CAS No.: 500-12-9
Synonyms: (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone
Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .
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Cat. No.: HY-N0243R
CAS No.: 4670-05-7
Theaflavin (Standard) is the analytical standard of Theaflavin. This product is intended for research and analytical applications. Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
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Cat. No.: HY-N10843
CAS No.: 112529-37-0
4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively .
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