117570-53-3
117570-53-3
Chemical Structure
Vadimezan
Synonym(s): DMXAA; ASA-404
- CAS No.: 117570-53-3
- Formula:C17H14O4
- Molecular Weight:282.29
IUPAC Name: 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
InChIKey: XGOYIMQSIKSOBS-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC=CC(C2=O)=C1OC3=C2C=CC(C)=C3C
Biological Activity: Vadimezan (DMXAA), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities.
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Vadimezan | 99.93% | Vadimezan (DMXAA), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities. | ||||||||||||||||||||
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Vadimezan (Standard) | ≥98% | Vadimezan (Standard) (DMXAA (Standard)) is the analytical standard of Vadimezan (HY-10964). This product is intended for research and analytical applications. Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-119340Mitoflaxone -
Similarity Score 0.63
HY-W5869609-Oxo-9H-xanthene-2,6-dicarboxylic acid -
Similarity Score 0.62
![Dibenzo[b,d]furan-4,6-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w243013.gif)
HY-W243013Dibenzo[b,d]furan-4,6-dicarboxylic acid -
Similarity Score 0.62
![2-(5-Oxo-5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w585894.gif)
HY-W5858942-(5-Oxo-5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid -
Similarity Score 0.62
HY-W5869619-Oxo-9H-xanthene-2,7-dicarboxylic acid -
Similarity Score 0.61
HY-10418AH 6809 -
Similarity Score 0.61
HY-N92192,5-Dihydroxyxanthone -
Similarity Score 0.61
HY-N101561,3,5-Trihydroxy-4-prenylxanthone -
Similarity Score 0.60
HY-W6653383,6-Dimethoxy-9H-xanthen-9-one -
Explore the MedChemAI to find more analogs
![Dibenzo[b,d]furan-4,6-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w243013.gif)
![2-(5-Oxo-5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w585894.gif)
