500-12-9
500-12-9
Chemical Structure
Goitrin
Synonym(s): (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone
- CAS No.: 500-12-9
- Formula:C5H7NOS
- Molecular Weight:129.18
IUPAC Name: (S)-5-vinyloxazolidine-2-thione
InChIKey: UZQVYLOFLQICCT-BYPYZUCNSA-N
SMILES: S=C1O[C@@H](C=C)CN1
Biological Activity: Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Goitrin | 99.66% | Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity. | ||||||||||||||||||||
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References
- [1]. Felker P, et, al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev. 2016 Apr;74(4):248-58. [Content Brief]
- [2]. Wooding S, et, al. Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010 Oct;35(8):685-92. [Content Brief]
- [3]. Nie LX, et, al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550. [Content Brief]
