Goitrin (Synonyms: (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone)

Cat. No.: HY-N0224A: FAQs
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Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity.

For research use only. We do not sell to patients.

Goitrin Chemical Structure

CAS No. : 500-12-9

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25 mg		Get quote	Estimated Time of Arrival: December 31

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Description	Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity^[1]^[2]^[3].
In Vitro	Goitrin (0.1-1 μM; 72 h) exhibits dose-dependent anti-influenza virus (H1N1) activity in Madin-Darby canine kidney (MDCK) cells, with an IC₅₀ of 0.19 μM^[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Goitrin Related Antibodies
Molecular Weight	129.18
Formula	C₅H₇NOS
CAS No.	500-12-9
SMILES	S=C1O[C@@H](C=C)CN1
Structure Classification	Others
Initial Source	Plants Brassicaceae cruciferous vegetables Endogenous metabolite
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Felker P, et, al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev. 2016 Apr;74(4):248-58. [Content Brief] [2]. Wooding S, et, al. Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010 Oct;35(8):685-92. [Content Brief] [3]. Nie LX, et, al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550. [Content Brief]

Goitrin Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Goitrin500-12-9(S)-Goitrin L-5-Vinyl-2-thiooxazolidoneInfluenza VirusglucosinolatemyrosinasethyroidperoxidaseiodineH1N1Inhibitorinhibitorinhibit

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Goitrin (Synonyms: (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone)

Other Forms of Goitrin:

Goitrin Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review