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2 Results for "
HIV-1 protease-IN-11
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "HIV-1 protease-IN-11" in MCE Product Catalog:
Cat. No.: HY-155690
CAS No.: 2925287-54-1
Target:
Research Areas:
HIV-1 protease-IN-11 (compound 34a) is a HIV-1 protease inhibitor with an IC50 of 0.41 nM. HIV-1 protease-IN-11 also exhibits significant activity against drug-resistant variant [1].
Cat. No.: HY-120812
CAS No.: 160729-91-9
Target:
Research Areas:
HIV-IN-11 is part of the hydroxylaminoglutaramide (HAPA) transition state isomeric series of HIV protease inhibitors and is a potent and selective inhibitor of HIV-1 protease. HIV-IN-11 competitively inhibits HIV-1 PR (Ki: 0.049 nM) and potently inhibits replication of HIV(IIIb)-infected MT4 lymphocytes at concentrations of 25.0-50.0 nM. HIV-IN-11 displays a longer half-life than indinavir sulfate in animal models and serves as a promising second-generation HIV protease inhibitor [1].
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