HIV-IN-11
HIV-IN-11 is part of the hydroxylaminoglutaramide (HAPA) transition state isomeric series of HIV protease inhibitors and is a potent and selective inhibitor of HIV-1 protease. HIV-IN-11 competitively inhibits HIV-1 PR (Ki: 0.049 nM) and potently inhibits replication of HIV(IIIb)-infected MT4 lymphocytes at concentrations of 25.0-50.0 nM. HIV-IN-11 displays a longer half-life than indinavir sulfate in animal models and serves as a promising second-generation HIV protease inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 160729-91-9
- Formula: C38H47N5O5
- Molecular Weight:653.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 160729-91-9
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Molecular Weight 653.81
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Formula C38H47N5O5
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SMILES
O=C([C@@H](C[C@@H](CN1[C@@H](CN(CC1)CC2=CN=C3OC=CC3=C2)C(NC(C)(C)C)=O)O)CC4=CC=CC=C4)N[C@@H]5[C@@H](CC6=C5C=CC=C6)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-IN-11 Related Classifications
HY-120812 Related Classifications
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