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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
HK2-IN-5
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "HK2-IN-5" in MCE Product Catalog:
Cat. No.: HY-189292
Research Areas:
HK2-IN-5 is a selective hexokinase 2 (HK2) inhibitor with an IC50 of 1.17 μM against HK2 enzymatic activity. HK2-IN-5 shows weak inhibition against HK3 and GCK (HK4). By inhibiting HK2, HK2-IN-5 induces a decrease in mitochondrial membrane potential (ΔΨm) and accumulation of reactive oxygen species (ROS), leading to mitochondrial dysfunction and oxidative stress, and its antiproliferative effect is mainly dependent on HK2. HK2-IN-5 can be used in research related to triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
