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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
208 Results for "
HP
" in MedChemExpress (MCE) Product Catalog:
Products (208)
208 Results for "HP" in MCE Product Catalog:
32
32 Publications Verification
Synonyms: (2-Hydroxypropyl)-β-cyclodextrin
5
5 Cited Publications
Target:
Research Areas:
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective (IC50>10 μM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux .
5
5 Cited Publications
Cat. No.: HY-15568A
Purity: 99.88%
Target:
Research Areas:
A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 sodium salt hydrate is highly selective (IC50>10 μM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 sodium salt hydrate reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux .
5
5 Cited Publications
Target:
3
3 Cited Publications
Target:
Research Areas:
JNJ-55308942 is a high-affinity, selective, brain-penetrant P2X7 functional antagonist (hP2X7: IC50=10 nM, Ki=7.1 nM; rP2X7: IC50=15 nM, Ki=2.9 nM). JNJ-55308942 is orally bioavailable, binds to brain P2X7 and blocks IL-1β release from adult rodent brain .
2
2 Cited Publications
Synonyms: MK-7264; AF-219
Target:
Research Areas:
Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis .
2
Target:
Research Areas:
Iloperidone (HP 873) is a D2/5-HT2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms .
2
2 Cited Publications
Synonyms: MK-7264 citrate; AF-219 citrate
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Research Areas:
Gefapixant citrate is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis .
2
2 Cited Publications
Cat. No.: HY-P70230
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HP; Haptoglobin Alpha(2FS)-Beta; Haptoglobin; Haptoglobin Alpha(1S)-Beta; Zonulin; HP Protein; Haptoglobin, Alpha Polypeptide; HP2ALPHA2; Haptoglobin, Beta Polypeptide; HPA1S
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P70099
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RARRES2; HP10433; Retinoic Acid Receptor Responder 2; Retinoic Acid Receptor Responder (Tazarotene Induced) 2; Chemerin; Tazarotene-Induced Gene 2 Protein; TIG2; RAR-Responsive Protein TIG2; Retinoic Acid Receptor Responder Protein 2
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P75553
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RARRES2; HP10433; Retinoic Acid Receptor Responder 2; Retinoic Acid Receptor Responder (Tazarotene Induced) 2; Chemerin; Tazarotene-Induced Gene 2 Protein; TIG2; RAR-Responsive Protein TIG2; Retinoic Acid Receptor Responder Protein 2
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P71089
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RNASE1; HP-RNase; Prev. RNS1; RNase A; RAC1; RIB-1; Ribonuclease, RNase A Family, 1 (Pancreatic); RIB1; Ribonuclease Pancreatic; Pancreatic Ribonuclease; Ribonuclease 1; Ribonuclease A C1; RNase UpI-1; Ribonuclease A; Ribonuclease A Family Member 1, Pancr
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72171
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DEFA1; Neutrophil Defensin 1; Prev. DEFA2; Defensin, Alpha 1; Prev. DEF1; HP-1; Prev. MRS; HP1; HNP-1; Myeloid-Related Sequence; Defensin, Alpha 1, Myeloid-Related Sequence; Defensin Alpha 1; Defensin, Alpha 2
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P75554
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RARRES2; HP10433; Retinoic Acid Receptor Responder 2; Retinoic Acid Receptor Responder (Tazarotene Induced) 2; Chemerin; Tazarotene-Induced Gene 2 Protein; TIG2; RAR-Responsive Protein TIG2; Retinoic Acid Receptor Responder Protein 2
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P7046
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T Cell And Mast Cell Growth Factor 40; Interleukin 9; P40 T-Cell And Mast Cell Growth Factor; IL-9; Interleukin-9; T-Cell Growth Factor P40; P40 Cytokine; HP40; Cytokine P40; P40
Species:
Human
Source:
CHO
Cat. No.: HY-W050088
CAS No.: 55453-87-7
Synonyms: HP 549
Target:
Research Areas:
Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases .
HP590 is an orally active, novel and potent STAT3 inhibitor (STAT3 luciferase activity: IC50=27.8 nM; ATP inhibition: IC50=24.7 nM). HP590 shows anti-proliferative activity to gastric cancer cells and induces apoptosis .
Cat. No.: HY-E70058
CAS No.: 37277-69-3
Synonyms: α-1-3,4 FucT; HP3/4FT
Target:
Research Areas:
alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (EC 2.4.1.65) (Hp3/4FT) can be found in Helicobacter pylori. alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) catalyzes fucose transfer from donor GDP-beta-l-fucose to the GlcNAc .
Cat. No.: HY-E70064A
Synonyms: HP3FT
Target:
Research Areas:
Helicobacter pylori alpha-1,3-fucosyltransferase (Hp3FT) catalyzes the glycosyl addition of fucose from the donor GDP-fucose to the acceptor N-acetyllactosamine .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
