2971855-37-3
2971855-37-3
Chemical Structure
HP590
- CAS No.: 2971855-37-3
- Formula:C29H24F6N4O3
- Molecular Weight:590.52
IUPAC Name: (4-(4-(2,2,2-trifluoroethoxy)benzyl)piperazin-1-yl)(4-(3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)phenyl)methanone
InChIKey: VFBJWQHKJOGQRX-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC1)CC2=CC=C(C=C2)OCC(F)(F)F)C3=CC=C(C=C3)C4=NC(C5=CC=C(C=C5)C(F)(F)F)=NO4
Biological Activity: HP590 is an orally active, novel and potent STAT3 inhibitor (STAT3 luciferase activity: IC50=27.8 nM; ATP inhibition: IC50=24.7 nM). HP590 shows anti-proliferative activity to gastric cancer cells and induces apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HP590 | 98.02% | HP590 is an orally active, novel and potent STAT3 inhibitor (STAT3 luciferase activity: IC50=27.8 nM; ATP inhibition: IC50=24.7 nM). HP590 shows anti-proliferative activity to gastric cancer cells and induces apoptosis. | ||||||||||||||||||||
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References
Keywords
