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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
90 Results for "
Helicobacter
" in MedChemExpress (MCE) Product Catalog:
Products (90)
90 Results for "Helicobacter" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: TAK-438 free base
Target:
Forschungsgebiete:
Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H +,K +-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori .
6
6 Publications Verification
Art. -Nr.: HY-100007A
CAS. Nr.: 1957202-44-6
Synonyms: TAK-438 hydrochloride
Target:
Forschungsgebiete:
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H +,K +-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori .
3
3 Cited Publications
Art. -Nr.: HY-B2196
CAS. Nr.: 84082-64-4
3
Category:
Entada phaseoloides (L.) Merr. Terpenoids Sesquiterpenes Plants Disease Research Fields Inflammation/Immunology Cancer Labiatae Extract
Target:
1
1 Cited Publications
Synonyms: Carbonyl diamide-13C
1
Target:
Forschungsgebiete:
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .
1
1 Cited Publications
HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei, Lactobacillus reuteri, and Bifidobacterium longum .
1
1 Cited Publications
Art. -Nr.: HY-P990209
Target:
Forschungsgebiete:
Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
1
1 Cited Publications
Art. -Nr.: HY-N2192
CAS. Nr.: 23445-00-3
Target:
Art. -Nr.: HY-W015551
CAS. Nr.: 3913-81-3
Synonyms: (E)-Dec-2-enal
Synonyms: TNP-2198
Rifasutenizol (TNP-2198) is a dual-targeted antibacterial agent that has a good antibacterial effect on Helicobacter pylori infection. Rifasutenizol can be used in the study of microaerophilic and anaerobic bacterial infections .
Art. -Nr.: HY-N5048
CAS. Nr.: 122965-41-7
Synonyms: 6'-O-Galloyl paeoniflorin
Art. -Nr.: HY-W003467
CAS. Nr.: 117977-21-6
Target:
Forschungsgebiete:
Rabeprazole Sulfide is a sulfide metabolite of Rabeprazole (HY-B0656). Rabeprazole Sulfide inhibits Helicobacter pylori motility. Rabeprazole Sulfide can be used for the research of Helicobacter pylori infection .
Forschungsgebiete:
Flurofamide is an effective bacterial urease inhibitor and antibacterial agent. Flurofamide inhibits urease and partially inhibits the chemotactic activity of Helicobacter pylori strain CPY3401. Flurofamide inhibits the growth of Ureaplasma urealyticum. Flurofamide reduces blood ammonia. Flurofamide can be used in the research of infectious urinary stones .
Art. -Nr.: HY-W039953
CAS. Nr.: 98924-81-3
Synonyms: N-azidoacetylglucosamine-tetraacylated
Target:
Forschungsgebiete:
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-containing fully acetylated N-acetylglucosamine analog, a metabolic glycan marker, and also an inducer of S-glycosylation. Ac4GlcNAz can be taken up by bacteria, processed via endogenous carbohydrate biosynthesis pathways, and integrated into glycans by replacing natural monosaccharides. Under alkali promotion, Ac4GlcNAz undergoes β-elimination to form α,β-unsaturated aldehydes, which then bind to cysteine residues via Michael addition. Ac4GlcNAz can be integrated into glycoproteins. Ac4GlcNAz is applicable to research related to Helicobacter pylori infection .
Synonyms: KRM-1648; ABI-1648
Target:
Forschungsgebiete:
Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) .
Art. -Nr.: HY-N3386
CAS. Nr.: 51847-92-8
Category:
Infection Flavonoids Monophenols Phenols Leguminosae Extract Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones
Target:
STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
