Bismuth subcitrate potassium

Name: Bismuth subcitrate potassium
Brand: MedChemExpress
SKU: HY-16102
Rating: 4.5 (1 reviews)

Cat. No.: HY-16102 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Bismuth subcitrate potassium is an antibiotic against 12 C. pyloridis strains with MIC₅₀ of 8 ug/ml. Bismuth subcitrate potassium is used to treat diseases of the upper gastrointestinal tract infected with Helicobacter pylori.

For research use only. We do not sell to patients.

Bismuth subcitrate potassium Chemical Structure

CAS No. : 880149-29-1

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Bismuth subcitrate potassium is an antibiotic against 12 C. pyloridis strains with MIC₅₀ of 8 ug/ml^[1]. Bismuth subcitrate potassium is used to treat diseases of the upper gastrointestinal tract infected with Helicobacter pylori^[2].

IC₅₀ & Target

MIC50: 8 ug/ml (C. pyloridis)^[1]

Clinical Trial

Molecular Weight

780.66

Formula

C₁₂H₈BiK₅O₁₄

CAS No.

880149-29-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Bi](OC(CC(C(O[K])=O)(O[K])CC(O[K])=O)=O)OC1=O)C(C1)(O[K])CC(O[K])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (128.10 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2810 mL	6.4049 mL	12.8097 mL
5 mM	0.2562 mL	1.2810 mL	2.5619 mL
10 mM	0.1281 mL	0.6405 mL	1.2810 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (273 KB) SDS (0 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. Van Caekenberghe DL, et al. In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori). Antimicrob Agents Chemother. 1987 Sep;31(9):1429-30. [Content Brief]

[2]. Malfertheiner P, et al. Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. Lancet. 2011 Mar 12;377(9769):905-13. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.2810 mL	6.4049 mL	12.8097 mL	32.0244 mL
	5 mM	0.2562 mL	1.2810 mL	2.5619 mL	6.4049 mL
	10 mM	0.1281 mL	0.6405 mL	1.2810 mL	3.2024 mL
	15 mM	0.0854 mL	0.4270 mL	0.8540 mL	2.1350 mL
	20 mM	0.0640 mL	0.3202 mL	0.6405 mL	1.6012 mL
	25 mM	0.0512 mL	0.2562 mL	0.5124 mL	1.2810 mL
	30 mM	0.0427 mL	0.2135 mL	0.4270 mL	1.0675 mL
	40 mM	0.0320 mL	0.1601 mL	0.3202 mL	0.8006 mL
	50 mM	0.0256 mL	0.1281 mL	0.2562 mL	0.6405 mL
	60 mM	0.0213 mL	0.1067 mL	0.2135 mL	0.5337 mL
	80 mM	0.0160 mL	0.0801 mL	0.1601 mL	0.4003 mL
	100 mM	0.0128 mL	0.0640 mL	0.1281 mL	0.3202 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.