880149-29-1
Chemical Structure
Bismuth subcitrate potassium
- CAS No.: 880149-29-1
- Formula:C12H8BiK5O14
- Molecular Weight:780.66
IUPAC Name: potassium 2-(2-((5-(carboxylatomethyl)-5-oxido-4,7-dioxo-1,3,2-dioxabismepan-2-yl)oxy)-2-oxoethyl)-2-oxidosuccinate
InChIKey: YDDTTXDPCSCLKY-UHFFFAOYSA-H
SMILES: O=C(O[Bi](OC(CC(C(O[K])=O)(O[K])CC(O[K])=O)=O)OC1=O)C(C1)(O[K])CC(O[K])=O
Biological Activity: Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis[1][2][3].
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Bismuth subcitrate potassium | 99.0% | Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis. | ||||||||||||||||||||
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Bismuth subcitrate potassium (Standard) | ≥98% | Bismuth subcitrate potassium (Standard) is the analytical standard of Bismuth subcitrate potassium (HY-16102). This product is intended for research and analytical applications. Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis. | ||||||||||||||||||||
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References
- [1]. Van Caekenberghe DL, et al. In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori). Antimicrob Agents Chemother. 1987 Sep;31(9):1429-30. [Content Brief]
- [2]. Malfertheiner P, et al. Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. Lancet. 2011 Mar 12;377(9769):905-13. [Content Brief]
- [3]. Hussar DA. New drugs: retapamulin, bismuth subcitrate potassium, and rotigotine. J Am Pharm Assoc (2003). 2007 Jul-Aug;47(4):539-43. [Content Brief]
