2. Membrane Transporter/Ion Channel
    Anti-infection
  3. Proton Pump
    Bacterial
  4. Rabeprazole Sulfide

Rabeprazole Sulfide 

Cat. No.: HY-W003467 Purity: 98.09%
COA Handling Instructions

Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment.

For research use only. We do not sell to patients.

Rabeprazole Sulfide Chemical Structure

Rabeprazole Sulfide Chemical Structure

CAS No. : 117977-21-6

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Solution
10 mM * 1 mL in DMSO USD 33 In-stock
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10 mM * 1 mL
ready for reconstitution
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Solid
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Based on 1 publication(s) in Google Scholar

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Description

Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment[1][2].

Molecular Weight

343.44

Appearance

Solid

Formula

C18H21N3O2S
CAS No.
SMILES

CC1=C(OCCCOC)C=CN=C1CSC2=NC3=CC=CC=C3N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (291.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9117 mL 14.5586 mL 29.1172 mL
5 mM 0.5823 mL 2.9117 mL 5.8234 mL
10 mM 0.2912 mL 1.4559 mL 2.9117 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 98.09%

COA (245 KB) HNMR (123 KB) RP-HPLC (97 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Rabeprazole Sulfide117977-21-6Proton PumpBacterialRabeprazolemetaboliteATPasepepticH. pyloriInhibitorinhibitorinhibit

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