3805 Results for "

Human Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (3805)

3805 Results for "Human Antibody" in MCE Product Catalog:

66
66 Publications Verification
Cat. No.: HY-P9907
CAS No.: 180288-69-1
Synonyms: Anti-Human HER2, Humanized Antibody
Trastuzumab is a humanized IgG1 monoclonal antibody that selectively binds to HER2 with high affinity. Trastuzumab can be used for the research of HER2-positive metastatic breast cancer and gastric cancer . (Note: The product specifications below only indicate the effective content of Trastuzumab. The component ratio of this product is Trastuzumab : excipients = 1:0.6-1:0.9.)
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66
66 Publications Verification
Cat. No.: HY-P9907A
CAS No.: 180288-69-1
Synonyms: Anti-Human HER2, Humanized Antibody (anti-HER2)

Target:  

ADC Antibodies EGFR

Research Areas:  

Cancer

Trastuzumab (anti-HER2) is a humanized IgG1 monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab (anti-HER2) has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research.
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62
62 Cited Publications
Cat. No.: HY-P9906
CAS No.: 216974-75-3
Synonyms: Anti-Human VEGF, Humanized Antibody
Bevacizumab (Anti-Human VEGF, Humanized Antibody) is a humanized monoclonal antibody against VEGF-A and an angiogenesis inhibitor. Bevacizumab blocks the interaction between VEGF-A and VEGF receptors. Bevacizumab possesses immunomodulatory properties. Bevacizumab can be used in research on metastatic colorectal cancer, metastatic breast cancer, and non-small cell lung cancer .
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55
55 Cited Publications
Cat. No.: HY-P9905
CAS No.: 205923-56-4
Synonyms: C225; IMC-C225
Research Areas:  

Cancer

Cetuximab (C225) is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a Kd of 0.201 nM for EGFR by SPR. Cetuximab has potent antitumor activity .
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45
45 Cited Publications
Cat. No.: HY-P9917
CAS No.: 375823-41-9
Synonyms: Anti-Human IL6R, Humanized Antibody; RG-1569; rhPM-1
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis . Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) .
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24
24 Cited Publications
Cat. No.: HY-P9903
CAS No.: 946414-94-4
Synonyms: BMS-936558; ONO-4538; MDX-1106

Target:  

PD-1/PD-L1

Research Areas:  

Infection Cancer

Nivolumab is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer.
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20
20 Cited Publications
Cat. No.: HY-P9908
CAS No.: 331731-18-1
Synonyms: Anti-Human TNF-alpha, Human Antibody; ABBV-3373 Antibody

Target:  

TNF Receptor Bacterial

Research Areas:  

Inflammation/Immunology Cancer

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
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20
20 Cited Publications
Cat. No.: HY-P99001

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Human IgG1 kappa, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1 kappa antibody .
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15
15 Cited Publications
Cat. No.: HY-108847
CAS No.: 185243-69-0
Purity:  99.20%

Target:  

TNF Receptor Bacterial

Research Areas:  

Inflammation/Immunology Cancer

Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis .
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14
14 Cited Publications
Cat. No.: HY-P9913
CAS No.: 174722-31-7
Synonyms: Anti-Human CD20 type I, Chimeric Antibody; HSDB 7455; IDEC-C2B8
Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer.
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12
12 Cited Publications
Cat. No.: HY-P9927A
CAS No.: 1229022-83-6

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .
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12
12 Cited Publications
Cat. No.: HY-P9927
CAS No.: 1229022-83-6
Synonyms: AIN457

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis .
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11
11 Cited Publications
Cat. No.: HY-108730
CAS No.: 1537032-82-8
Synonyms: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Avelumab (Anti-Human PD-L1) a fully human IgG1 anti-PD-L1 monoclonal antibody (mAb) with potential antibody-dependent cell-mediated cytotoxicity (ADCC). Avelumab enhances ADCC on several cancer cell lines expressing PD-L1. Avelumab can be used for the study of chordoma .
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11
11 Cited Publications
Cat. No.: HY-P9915
CAS No.: 945721-28-8
Synonyms: Anti-Human CD38, Human Antibody; HuMax-CD38; JNJ-54767414

Target:  

CD38 ADC Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Daratumumab (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab has anti-multiple myeloma (MM) effect. Daratumumab impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition .
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11
11 Cited Publications
Cat. No.: HY-P9915A
CAS No.: 945721-28-8
Synonyms: Anti-Human CD38, Human Antibody (PBS)

Target:  

ADC Antibodies CD38

Research Areas:  

Cancer

Daratumumab (PBS) (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab (PBS) has anti-multiple myeloma (MM) effect. Daratumumab (PBS) impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition .
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11
11 Cited Publications
Cat. No.: HY-108730A
CAS No.: 1537032-82-8
Purity:  96.02%

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Avelumab (anti-PD-L1) a fully human IgG1 anti-PD-L1 monoclonal antibody (mAb) with potential antibody-dependent cell-mediated cytotoxicity (ADCC). Avelumab (anti-PD-L1) enhances ADCC on several cancer cell lines expressing PD-L1. Avelumab (anti-PD-L1) can be used for the study of chordoma .
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11
11 Cited Publications
Cat. No.: HY-P99003

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Human IgG4 (S228P) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG4κ antibody.
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11
11 Cited Publications
Cat. No.: HY-K0214

MCE Protein G Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein G, effectively purifies mammalian monoclonal and polyclonal antibodies, such as human IgG3 and rat IgG2a.

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10
10 Cited Publications
Cat. No.: HY-P80438
Synonyms: A26C1A Antibody; A26C1B Antibody; ACTB Antibody; ACTB_Human Antibody; Actin beta Antibody; Actin cytoplasmic 1 Antibody; Actin, cytoplasmic 1, N-terminally processed Antibody; Actx Antibody; b actin Antibody; Beta cytoskeletal actin Antibody; Beta-actin Antibody; BRWS1 Antibody; E430023M04Rik Antibody; MGC128179 Antibody; PS1TP5 binding protein 1 Antibody; PS1TP5BP1 Antibody; β-actin Antibody

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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9
9 Cited Publications
Cat. No.: HY-138298
CAS No.: 1826843-81-5
Purity:  98.90%
Synonyms: T-DXd (solution); DS-8201 (solution); DS-8201a (solution)
Trastuzumab deruxtecan (T-DXd; DS-8201a) (solution) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer .
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