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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
IBR 120
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "IBR 120" in MCE Product Catalog:
Cat. No.: HY-176549A
CAS No.: 1704699-99-9
Research Areas:
IBR120 is a RAD51 inhibitor. IBR120 inhibits homologous recombination (HR) repair and attenuates RAD51-DNA interaction by binding to the hydrophobic pocket of the RAD51 core domain and disrupting RAD51 multimerization. IBR120 induces apoptotic cell death and inhibits the proliferation of a broad spectrum of cancer cell lines. IBR120 in combination with anticancer agents such as EGFR inhibitors and microtubule agents produces synergistic anti-proliferative effects. IBR120 can be used in research related to breast cancer, chronic myeloid leukemia, osteosarcoma, cervical cancer, and glioblastoma .
Cat. No.: HY-176549
CAS No.: 1996673-44-9
(Rac)-IBR120 is the racemate of IBR120 (HY-176549A). IBR120 is a RAD51 inhibitor that has significant growth inhibition activity against MDA-MB-468 cells. (Rac)-IBR120 can be used for the research of difficult-to-treat cancers like triple negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
