309 Results for "

Interleukin-1

" in MedChemExpress (MCE) Product Catalog:
Products (309)

309 Results for "Interleukin-1" in MCE Product Catalog:

58
58 Publications Verification
Referencia número: HY-P7028
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; PreInterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
loading...
    loading...
56
56 Cited Publications
Referencia número: HY-108841
No. CAS: 143090-92-0
Pureza:  99.40%
Synonyms: Kineret; Anakinra

Target:  

Interleukin Related

Áreas de investigación:  

Infection Inflammation/Immunology Cancer

Raleukin (Kineret) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction [1] .
loading...
    loading...
45
45 Cited Publications
Referencia número: HY-P7073
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; PreInterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
23
23 Cited Publications
Referencia número: HY-P7097
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; PreInterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Rat
Source:  
E. coli
loading...
    loading...
22
22 Cited Publications
Referencia número: HY-P80622
Synonyms: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-F, IHC-P, ELISA

Reactivity:  

Human, Mouse

loading...
    loading...
14
14 Cited Publications
Referencia número: HY-P7218
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; Chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; Interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; Interleukin-33; IL-1F11; DVS27; NFEHEV; Nuclear Factor From High Endothelial Venules; IL-33
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
11
11 Cited Publications
Referencia número: HY-13329
No. CAS: 509093-47-4
Pureza:  99.90%
Synonyms: IRAK-1/4 Inhibitor I
Target:  

IRAK

Áreas de investigación:  

Inflammation/Immunology

IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.2 μM and 0.3 μM, respectively.
loading...
    loading...
10
10 Cited Publications
Referencia número: HY-19975
No. CAS: 946387-07-1
Target:  

TRP Channel

Áreas de investigación:  

Neurological Disease Cancer

RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM) [1]. RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells .
loading...
    loading...
9
9 Cited Publications
Referencia número: HY-P72566
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; Interleukin 1 Receptor Antagonist; Intracellular Interleukin-1 Receptor Antagonist (IcIL-1ra); ICIL-1RA; Intracellular Interleukin-1 Receptor Antagonist; IL-1RN; Intracellular IL-1 Receptor Antagonist Type II; IL1RA; Type II Interleukin-1 R
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
9
9 Cited Publications
Referencia número: HY-P73149
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; PreInterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
loading...
    loading...
7
7 Cited Publications
Referencia número: HY-P81232
Synonyms: caspase-1 isoform alpha subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
7
7 Cited Publications
Referencia número: HY-19836
No. CAS: 1817626-54-2
Synonyms: PF-06650833
Target:  

IRAK

Áreas de investigación:  

Inflammation/Immunology

Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas [1] .
loading...
    loading...
6
6 Cited Publications
Referencia número: HY-103017
No. CAS: 2591344-30-6
Pureza:  99.14%
Target:  

IRAK

Áreas de investigación:  

Infection

JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice [1].
loading...
    loading...
6
6 Cited Publications
Referencia número: HY-P7073A
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; PreInterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Mouse
Source:  
CHO
loading...
    loading...
6
6 Cited Publications
Referencia número: HY-103017A
No. CAS: 2227368-54-7
Pureza:  99.03%
Target:  

IRAK

Áreas de investigación:  

Infection Inflammation/Immunology Cancer

JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice [1]. JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM .
loading...
    loading...
6
6 Cited Publications
Referencia número: HY-P1110
No. CAS: 185413-30-3
Target:  

Interleukin Related

Áreas de investigación:  

Inflammation/Immunology

AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo [1].
loading...
    loading...
5
5 Cited Publications
Referencia número: HY-P7027
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1A; IL-1A; Prev. IL1; PreInterleukin 1 Alpha; IL1F1; Interleukin-1 Alpha; Hematopoietin-1; IL-1 Alpha; IL1-ALPHA; Interleukin 1 Alpha; Pro-Interleukin-1-Alpha
Species:  
Human
Source:  
E. coli
loading...
    loading...
5
5 Cited Publications
Referencia número: HY-P7029
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; Interleukin 1 Receptor Antagonist; Intracellular Interleukin-1 Receptor Antagonist (IcIL-1ra); ICIL-1RA; Intracellular Interleukin-1 Receptor Antagonist; IL-1RN; Intracellular IL-1 Receptor Antagonist Type II; IL1RA; Type II Interleukin-1 R
Species:  
Human
Source:  
E. coli
loading...
    loading...
5
5 Cited Publications
Referencia número: HY-P73900
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; PreInterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Rat
Source:  
E. coli
loading...
    loading...
5
5 Cited Publications
Referencia número: HY-P80587
Synonyms: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Host:  

Rabbit

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human, Mouse, Rat

loading...
    loading...