1 Result for "

JB6 P+ mouse epidermal cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JB6 P+ mouse epidermal cells" in MCE Product Catalog:

Cat. No.: HY-122859
CAS No.: 2252153-94-7
Target:  

TOPK ERK p38 MAPK JNK AP-1

Research Areas:  

Inflammation/Immunology

ADA-07 is a TOPK inhibitor with activity at the ATP-binding pocket that does not inhibit MEK1 activity. ADA-07 suppresses solar ultraviolet (SUV)-induced phosphorylation of ERK1/2, p38, and JNKs, and inhibits AP-1 activity. ADA-07 attenuates tumor incidence, multiplicity, and volume in SUV-exposed SKH-1 hairless mice. ADA-07 can be used for the research of solar ultraviolet-induced skin carcinogenesis .
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