9 Results for "

LPS-induced BV2 microglial cells

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "LPS-induced BV2 microglial cells" in MCE Product Catalog:

Cat. No.: HY-N8371
CAS No.: 142279-40-1
Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression .
loading...
    loading...
Cat. No.: HY-N15566
Theleganbanin D is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin D inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin D is promising for research of neurodegenerative diseases .
loading...
    loading...
Cat. No.: HY-155572
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

Nrf2 activator-8 (compound 10e) is a Nrf2 activator (EC50=37.9 nM). Nrf2 activator-8 exhibits remarkable antioxidant and anti-inflammatory effects in BV-2 microglial cells. Nrf2 activator-8 can significantly restore spatial memory deficits in a mouse model of lipopolysaccharide (LPS)-induced neuroinflammation .
loading...
    loading...
Cat. No.: HY-N15570
CAS No.: 121254-55-5
2-O-Methylatromentin is an anti-neuroinflammatory agent. 2-O-Methylatromentin shows inhibitory activity on the production of pro-inflammatory cytokines TNF-α, IL-6 and IL-1β in Lipopolysaccharides (HY-D1056) (LPS) -induced BV-2 microglial cells. 2-O-Methylatromentin can be used for the study of neuroinflammatory related diseases .
loading...
    loading...
Cat. No.: HY-N13831
CAS No.: 2721-56-4
Swietenidine B is a quinoline alkaloid that can be isolated from the root bark of Dictamnus dasycarpus. Swietenidine B does not show significant activity in inhibiting NO production in LPS-induced BV-2 microglial cells .
loading...
    loading...
Cat. No.: HY-N21923
CAS No.: 126239-88-1
Euphoscopin H is a diterpenoid compound found in the fresh leaves and roots of Euphorbia helioscopia. Euphoscopin H shows weak inhibitory activity against LPS-induced NO production and no obvious cytotoxicity in the mouse microglial BV-2 cell model .
loading...
    loading...
Cat. No.: HY-N15564
CAS No.: 31554-34-4
Theleganbanin B is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin B inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin B inhibits the phosphorylation of JAK2/STAT3. Theleganbanin B is promising for research of neurodegenerative diseases .
loading...
    loading...
Cat. No.: HY-N13729
CAS No.: 2376309-57-6
Stephalonine P is a hasubanan-type alkaloid anti-inflammatory agent with neuroprotective effects against neuroinflammation. Stephalonine P regulates post-ischemic inflammatory responses by inhibiting NO production in LPS-activated BV2 microglia (IC50=34.01 μM), thereby reducing microglial activation and neuronal damage. Stephalonine P can be isolated from the whole plant of Stephania japonica. Stephalonine P can be used in research on stroke and other neuroinflammation-related diseases .
loading...
    loading...
Cat. No.: HY-N6998A
CAS No.: 435278-17-4
6-epi-Paederosidic acid is a cyclopentanoid monoterpene glycoside found in the aerial parts of Paederia foetida L. 6-epi-Paederosidic acid does not exhibit cytotoxic activity against human tumor cells, hepatoprotective activity against APAP (HY-66005)-induced cellular toxicity, or inhibitory activity against LPS (HY-D1056)-induced nitric oxide production in murine microglia .
loading...
    loading...