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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
MEF-AXL cells
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "MEF-AXL cells" in MCE Product Catalog:
Cat. No.: HY-184433
CAS No.: 2758062-71-2
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Axl-IN-22 is a selective, orally active dual inhibitor of AXL/MER, with IC50 values of 13 nM and 10 nM, respectively. Axl-IN-22 functionally inhibits AXL kinase activity, including ligand-independent autophosphorylation, and blocks the downstream PI3K/AKT signaling pathway, with excellent selectivity over TYRO3, IGF1R and INSR. Axl-IN-22 inhibits tumor growth in vivo and produces a synergistic effect when combined with anti-PD-1 antibody. Axl-IN-22 can be used in studies related to malignant tumors, leukemia, colon cancer and non-small cell lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
