8 Results for "

Melanogenesis inhibition

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Melanogenesis inhibition" in MCE Product Catalog:

Cat. No.: HY-N2073
CAS No.: 1191-41-9
Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects .
loading...
    loading...
Cat. No.: HY-N2232
CAS No.: 66648-44-0
Synonyms: N-trans-Feruloyloctopamine
N-trans-feruloyloctopamine is a natural hydroxycinnamic acid amide compound derived from garlic outer skin, possessing tyrosinase inhibition, FGF2 inhibition, anti-melanogenic, and anti-tumor activities. N-trans-feruloyloctopamine inhibits tyrosinase activity and downregulates tyrosinase mRNA and protein expression (IC50 = 5.3 μM), and inhibits melanogenesis in α-MSH-stimulated B16F10 cells . N-trans-feruloyloctopamine inhibits Akt and p38 MAPK phosphorylation, binds to E-cadherin to block EMT, reduces Slug, inhibits hepatocellular carcinoma invasion, and induces hepatocellular carcinoma cell apoptosis. N-trans-feruloyloctopamine can be used in research related to hepatocellular carcinoma, pigmentation disorders, and UVB-induced skin damage .
loading...
    loading...
Cat. No.: HY-N3425
CAS No.: 1238116-48-7
Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMPK activation .
loading...
    loading...
Cat. No.: HY-117761
CAS No.: 1393371-39-5
Target:  

PPAR

Research Areas:  

Metabolic Disease Cancer

MHY908 is a potent dual agonist of PPARα and PPARγ . MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity .
loading...
    loading...
Cat. No.: HY-N2073S
CAS No.: 203633-16-3
Ethyl linolenate-d5 is the deuterium labeled Ethyl linolenate. Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects .
loading...
    loading...
Cat. No.: HY-126618
CAS No.: 670225-69-1
Aspochalasin I exhibits cytotoxicity against cancer cells NCIH460, MCF-7 and SF-268, with IC50s of 22.1, 33.4 and 19.9 μM. Aspochalasin I inhibits melanogenesis (IC50 of 22.4 μM) through inhibition of tyrosinase, and can thus be used as whitening agent .
loading...
    loading...
Cat. No.: HY-N3810
CAS No.: 57719-81-0
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds .
loading...
    loading...
Cat. No.: HY-179619
Target:  

Tyrosinase

Research Areas:  

Metabolic Disease

Tyrosinase-IN-46 (Compound III19) is a tyrosinase inhibitor. Its IC50 values for L-dopa and L-tyrosine are 3.24 and 2.79 nM respectively. Tyrosinase-IN-46 inhibits melanin synthesis and shows a significant anti-pigmentation effect. Tyrosinase-IN-46 can be used for the study of pigmentation disorders .
loading...
    loading...