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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
133 Results for "
N-Glycan
" in MedChemExpress (MCE) Product Catalog:
Products (133)
133 Results for "N-Glycan" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P2929
CAS No.: 83534-39-8
Research Areas:
PNGase F, a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F removes nearly all N-linked oligosaccharides from glycoproteins. PNGase F can release N-glycans from glycoproteins in glycoanalytical workflows .
2
2 Cited Publications
Cat. No.: HY-P2929C
CAS No.: 83534-39-8
Research Areas:
PNGase F (Lyophilized), a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F (Lyophilized) removes nearly all N-linked oligosaccharides from glycoproteins. PNGase F (Lyophilized) can release N-glycans from glycoproteins in glycoanalytical workflows .
2
2 Cited Publications
Cat. No.: HY-P2929B
CAS No.: 83534-39-8
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PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum .
2
2 Cited Publications
Cat. No.: HY-P2929A
CAS No.: 83534-39-8
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PNGase F-Fast is a glycosidase that catalyzes the cleavage of internal glycosidic bonds in oligosaccharides. PNGase F-Fast removes almost all N-linked oligosaccharides from glycoproteins. PNGase F-Fast can release N-glycans from glycoproteins in the sugar analysis workflow. The cleavage site is: the glycosidic bond between the innermost N-acetylglucosamine and asparagine. PNGase F-Fast is an improved reagent that allows for rapid deglycosylation of antibodies and antibody fusions within minutes .
2
2 Cited Publications
Cat. No.: HY-P2929D
CAS No.: 83534-39-8
Target:
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PNGase F (MS grade), a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F (MS grade) removes nearly all N-linked oligosaccharides from glycoproteins. PNGase F (MS grade) can be used for MS analysis .
1
1
1 Cited Publications
Cat. No.: HY-163121
CAS No.: 1096144-06-7
Research Areas:
PST3.1a is an orally active and brain-penetrant N-acetylglucosamine glycosyltransferase (MGAT5) inhibitor with a human IC50 of 2 µM. PST3.1a inhibits TGFβR and FAK signaling pathway activity. PST3.1a alters β1,6-GlcNAc N-glycans and microtubule/microfilament integrity, increases OLIG2 expression, and inhibits proliferation, migration, invasiveness, and clonogenic capacities of glioblastoma initiating cells. PST3.1a reduces invasive and proliferative capacity of glioblastoma initiating cells in orthotopic graft models, increases overall survival of orthotopic graft model mice. PST3.1a blunts MGAT5 overexpression, decreases renal fibrosis via collagen 1, collagen 4, and galectin 3 downregulation in a rat chronic kidney disease model. PST3.1a can be used for the research of glioblastoma multiforme and chronic kidney disease .
Cat. No.: HY-E70555
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PNGase A is a β-aspartylglucosaminidase and N-glycan-releasing enzyme. PNGase A catalyzes hydrolysis reactions to release the N-glycan moiety from glycoproteins or glycopeptides. PNGase A releases N-linked oligosaccharides containing core α-1,3 fucose from glycopeptides. PNGase A undergoes self-deglycosylation, which may cause contamination of endogenous glycan structures in N-glycan analysis. PNGase A cannot be heterologously expressed in recombinant expression systems; it can be extracted and purified from almond seeds .
Cat. No.: HY-148390
CAS No.: 67299-24-5
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Sialylglyco peptide is a N-Glycan and sialate glycopeptide .
Cat. No.: HY-N10630
CAS No.: 103584-68-5
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G-NGA2 N-Glycan is a N-Glycan, and can be used for labeling and modification of proteins.
Cat. No.: HY-156905
CAS No.: 1202854-87-2
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6-Azido-N-acetylgalactosamine-UDP (Compound 5) is a 6-azido-modified nucleotide sugar. It acts as an active sugar donor in lactose glycosylation catalyzed by beta-1,3-N-Acetylhexaminyltransferase (LgtA). Azido-modified nucleotide sugars are strategically used in copper-free click chemistry to modify the N-glycan core structure of IgG .
Cat. No.: HY-N10628
CAS No.: 1125602-44-9
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Target:
Cat. No.: HY-N10626
CAS No.: 125139-41-5
Category:
Target:
Cat. No.: HY-E70132
CAS No.: 37278-88-9
Synonyms: Endo D
Target:
Research Areas:
Endo-β-N-acetylglucosaminidase D (Endo D), isolated from Streptococcus pneumoniae. Endo-β-N-acetylglucosaminidase D hydrolyzes Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-β-N-acetylglucosaminidase D possesses transglycosylation activity with sugar oxazoline as the donor substrate .
Cat. No.: HY-N10631
CAS No.: 70858-45-6
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Paucimannose is a mannosidic N-glycan epitope. It acts as a carcinoembryonic antigen, and a marker for cancer, stem cell properties and inflammation. Paucimannose mainly exists in plants and invertebrates. It consists of oligomannose-type N-glycans that preferentially bind to mannose-binding lectin. Paucimannose localizes on the surface of resting cells and translocates upon cell activation. It can be used in studies related to Pseudomonas aeruginosa infection, cancer and pancreatitis .
Cat. No.: HY-158482
Synonyms: Mannose-3 N-linked oligosaccharide; Oligomannose 3 Glycan
Cat. No.: HY-16304
CAS No.: 27251-84-9
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
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G0 N-glycan-Asn is a glycopeptide. G0 N-glycan-Asn can be used for various biochemical studies .
Cat. No.: HY-E70879
Synonyms: EndoM N175Q
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Endoglycosidase M (N175Q mutant) (EndoM N175Q) can transfer natural N-glycans or oxazoline N-glycans to any peptide or protein with a GlcNAc residue to form a β1-4-glycosidic linkage. Endoglycosidase M (N175Q mutant) is a useful tool in the synthesis of homogeneous glycopeptides and glycoproteins .
Cat. No.: HY-W540687
CAS No.: 58902-60-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
