14 Results for "

Non-ribosomal peptide

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Non-ribosomal peptide" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-112862
CAS No.: 301351-95-1
Purity:  ≥98.0%
Research Areas:  

Infection

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
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Cat. No.: HY-W142073
CAS No.: 17332-70-6
Synonyms: 7-Methyltryptophan
Research Areas:  

Infection

7-Methyl-DL-tryptophan (7-Methyltryptophan) is an amino acid derivative, which is a key precursor for biosynthesis of many non-ribosomal peptide antibiotics. 7-Methyl-DL-tryptophan plays an important role in synthesis of high-efficiency antibacterial agents and analogues thereof .
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Cat. No.: HY-W073762
CAS No.: 2241669-86-1
Research Areas:  

Cancer

FBnG is a component of non-ribosomal peptide synthetase/polyketide synthase (NRPS/PKS), which is associated with the biosynthesis of fabrubactin (FBN). FBnG can be used for synthesis of AUTAC4 as part of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 (HY-150408) .
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Cat. No.: HY-100710
CAS No.: 186692-73-9
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Epothilone C is a polyketide natural product. Epothilone C is produced by the combined action of one nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) modules in a multienzyme system. Epothilone C can be used for tumor research .
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Cat. No.: HY-P11040
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Peptide P2.2, a non-ribosomal peptide, is an antimicrobial peptide. Peptide P2.2 has potent antibacterial activity with MIC50s of 4 and 32 μM for V. parahaemolyticus and V. alginolyticus, respectively. Peptide P2.2 increases synergistic antibacterial effects with antibiotics (such as Ofloxacin (HY-B0125) and Linezolid (HY-10394)) with negligible hemolytic activity. Peptide P2.2 disrupts bacterial membranes and increases permeability by modulating proteins involved in the type VI and III secretion systems. Peptide P2.2 can be used for bacterial infections research .
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Cat. No.: HY-162371
Research Areas:  

Infection

NRPSs-IN-1 (Compound 7) is a cell-penetrating inhibitor of non-ribosomal peptide synthetase (NRPSs). NRPSs-IN-1 K inhibits gramicidin S synthetase A (GrsA) with a Kd value of 16.6 nM .
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Cat. No.: HY-P5707
CAS No.: 4422-52-0
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Gramicidin B is a nonribosomal peptide antibiotic .
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Cat. No.: HY-121459
CAS No.: 22862-63-1
Target:  

HSP Ras

Neoantimycin is a GRP78/BiP and K-Ras regulator with anticancer activity. Its biosynthesis is catalyzed by a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system .
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Cat. No.: HY-130043
CAS No.: 956904-34-0
11-O-Methylpseurotin A is a compound of mixed polyketide synthase–nonribosomal peptide synthetase (PKS/NRPS) origin. 11-O-Methylpseurotin A selectively inhibits a Hof1 deletion strain .
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Cat. No.: HY-153859
CAS No.: 322650-05-5
Research Areas:  

Others

Ser-SNAC TFA is a small-molecule substrate for NRPS C domains. As for NRPSs, refers to nonribosomal peptide synthetases, are large multidomain proteins to catalyze the formation of biologically active natural products. Ser-SNAC TFA can be used for characterizing the substrate specificity of C domain-catalyzed peptide bond formation .
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Cat. No.: HY-N13942
CAS No.: 444300-73-6
Target:  

Others

Argyrin E is a natural cyclic, non-ribosomal peptide .
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Cat. No.: HY-N13945
CAS No.: 444300-75-8
Target:  

Others

Argyrin G is a natural cyclic, non-ribosomal peptide .
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Cat. No.: HY-N13948
CAS No.: 444300-76-9
Target:  

Others

Argyrin H is a natural cyclic, non-ribosomal peptide .
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Cat. No.: HY-W722245
CAS No.: 79236-62-7
Pyochelin is a salicylate-based nonribosomal peptide siderophore produced by Pseudomonas aeruginosa. Pyochelin chelates Fe 3+ and transports it back into bacterial cells, providing the iron essential for bacterial survival. Pyochelin can also chelate other metals such as Zn 2+, Co 2+, and Ni 2+, which helps bacteria maintain intracellular metal ion homeostasis by chelating and excreting excess metals in response to toxic metal stress. Pyochelin can be used in studies related to Pseudomonas aeruginosa infection .
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