2 Results for "

OCI-LY19 cell

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "OCI-LY19 cell" in MCE Product Catalog:

Cat. No.: HY-100847
CAS No.: 1825345-52-5
Target:  

PARP

Research Areas:  

Cancer

AZ0108 is an inhibitor for poly ADP-ribose polymerase (PARP), which inhibits PARP1, PARP2, PARP3, PARP6, TNKS1, TNKS2, with IC50s of <0.03, <0.03, 2.8, 0.083, 3.2, >3 μM, respectively. AZ0108 prevents centrosome clustering with an EC50 of 0.053 μM, and exhibits cytotoxicity in cell OCI-LY-19 with GI50 of 0.017 μM. AZ0108 exhibits good in vivo pharmacokinetic characters in rat/mouse models .
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Cat. No.: HY-147570
CAS No.: 2766407-55-8
Target:  

ATM/ATR

Research Areas:  

Cancer

ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity .
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