ATR-IN-18
ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2766407-55-8
- Formula: C19H22F3N7O5S
- Molecular Weight:517.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ATR 0.69 nM (IC50) |
Chemical Information
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CAS No. 2766407-55-8
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Molecular Weight 517.48
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Formula C19H22F3N7O5S
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SMILES
OC(C(F)(F)F)=O.CS(=O)(N1C2=C(CC1)C(N3[C@@H](COCC3)C)=NC4=C2C=NN4C5=NNC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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