1 Result for "

PQ401

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PQ401" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-13686
CAS No.: 196868-63-0
Purity:  99.85%
Target:  

IGF-1R Apoptosis

Research Areas:  

Cancer

PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis .
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