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Radiopharmaceutical

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Biochemical Assay Reagents (11) Drug Derivative (1) Drug Intermediate (4) Drug Isomer (1) Endogenous Metabolite (1) FAP (1) MOFs (1) Neurokinin Receptor (1) Organoid (1) PSMA (1) Radionuclide-Drug Conjugates (RDCs) (8) Reference Standards (4) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (1) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-129040A

m-Iodobenzylguanidine sulfate 1 Publications Verification MIBG sulfate; Iobenguane sulfate	Adrenergic Receptor	Cancer
m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .

HY-129650

Florbetapir 1 Publications Verification AV-45; Flobetapir	Biochemical Assay Reagents	Others
Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 .

HY-W102590

DOTMP	Biochemical Assay Reagents	Others
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-B1684

Mebrofenin SQ 26962	Biochemical Assay Reagents	Others
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

HY-159770A

(S)-EB-FAPI-B2	Radionuclide-Drug Conjugates (RDCs)	Cancer
(S)-EB-FAPI-B2 (Compound II-11) is a precursor for radiopharmaceutical labeling, which can be combined with radionuclides to create radionuclide drug conjugates (RDCs). RDCs have the capability to specifically target biomolecules and can be used in medical imaging .

HY-126369

Exametazime HM-PAO	Biochemical Assay Reagents	Others
Exametazime (HM-PAO) is a lipophilic agent used for the preparation of brain imaging radiopharmaceuticals. ⁹⁹Tcm-Exametazime is an effective in vitro leukocyte labeling agent .

HY-P10369

Betiatide	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Cardiovascular Disease Inflammation/Immunology
Betiatide, as a chelating agent for Technetium-99m ( ^99mTc), is used to prepare ^99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi . Betiatide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-W004649

Tris-BOC-cyclen	Biochemical Assay Reagents	Others
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W109978

Tetrabutylammonium perrhenate	Biochemical Assay Reagents	Others
Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.

HY-P11088

VCAM1 binding peptide	Transmembrane Glycoprotein Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology
VCAM1 binding peptide is a VCAM1 binder with internalization activity. VCAM1 binding peptide can be labeled with 5-FAM. VCAM1 binding peptide serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide is applicable to studies related to atherosclerosis .

HY-159771

FAP6-19	FAP	Cancer
FAP6-19 is a fibroblast activation protein (FAP) targeting radioligand with a K_d of 18.2 nM. FAP6-19 selectively delivers therapeutic radioactive nuclides (such as 177Lu) to the tumor site by targeting the overexpressed FAP protein in the tumor microenvironment, achieving precise killing of cancer cells while minimizing radiation damage to healthy tissues. FAP6-19 exhibits extremely high total cellular uptake and good intracellular retention ability in HT1080 cells. After being labeled with 111In, FAP6-19 produced extremely high tumor/kidney and tumor/liver dose ratios in the mouse model with 4T1 tumors. FAP6-19 can be used in the research of solid tumors expressing FAP.

HY-W143890

Etifenin EHIDA	Biochemical Assay Reagents	Neurological Disease Metabolic Disease
Etifenin can be used for production of non-toxic radiopharmaceuticals which are in regular radiodiagnostic use .

HY-159767A

(S)-DOTAGA.(SA.FAPi)2	Radionuclide-Drug Conjugates (RDCs)	Cancer
(S)-DOTAGA.(SA.FAPi)2 is a precursor for radiopharmaceutical labeling, which can be combined with radionuclides to create radionuclide drug conjugates (RDCs). RDCs have the capability to specifically target biomolecules and can be used in medical imaging .

HY-W402032

Bis-Cbz-cyclen	Biochemical Assay Reagents	Others
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-129650R

Florbetapir (Standard) AV-45 (Standard); Flobetapir (Standard)	Biochemical Assay Reagents Reference Standards	Others
Flobetapir (Standard) (AV-45 (Standard)) is the analytical standard of Flobetapir (HY-129650). This product is intended for research and analytical applications. Flobetapirmay is a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound.

HY-W009310R

9-cis-Retinal (Standard)	Reference Standards Endogenous Metabolite Organoid	Others
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

HY-129040AR

m-Iodobenzylguanidine sulfate (Standard) MIBG sulfate (Standard); Iobenguane sulfate (Standard)	Adrenergic Receptor Reference Standards	Cancer
m-Iodobenzylguanidine (sulfate) (Standard) is the analytical standard of m-Iodobenzylguanidine (sulfate). This product is intended for research and analytical applications. m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .

HY-B1684R

Mebrofenin (Standard) SQ 26962 (Standard)	Biochemical Assay Reagents Reference Standards	Others
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

HY-167987

Guraxetan-NH-PEG3-TFP ester	Radionuclide-Drug Conjugates (RDCs)	Cancer
Guraxetan-NH-PEG3-TFP ester (Fig.3) is a chelating agent and linker conjugate that can be used in the synthesis of radiopharmaceuticals .

HY-167789

DOTA(tBu3)-PEG4-TFP	Radionuclide-Drug Conjugates (RDCs)	Cancer
DOTA(tBu3)-PEG4-TFP is a chelating agent and linker conjugate that can be used in the synthesis of radiopharmaceuticals .

HY-167790

2,3,5,6-Tetrafluorophenyl propionate-PEG3-amino-tetraxetan	Radionuclide-Drug Conjugates (RDCs)	Cancer
2,3,5,6-Tetrafluorophenyl propionate-PEG3-amino-tetraxetan is a chelating agent and linker conjugate that can be used in the synthesis of radiopharmaceuticals .

HY-185120

ProX1-(SS)-DOTAGA_R	Radionuclide-Drug Conjugates (RDCs) Drug Intermediate	Cancer
ProX1-(SS)-DOTAGA_R (Compound 25a) is the unbound radionuclide portion of the radiopharmaceutical and can be used for targeted delivery to diseases characterized by ACP3 expression .

HY-153130

(S)-Zadavotide guraxetan (S)-PSMA I&T; (S)-PNT-2002	Drug Isomer PSMA	Cancer
(S)-Zadavotide guraxetan ((S)-PSMA I&T) is the S-isomer of EuK-Sub-kf-iodo-y-DOTAGA. (S)-Zadavotide guraxetan is a PSMA targeting compound .

HY-185401

ATSM	MOFs	Cancer
ATSM is a ligand that forms complexes with Cu ²⁺, Ni ²⁺, Zn ²⁺, and Fe ²⁺, with the highest affinity for Cu ²⁺. ATSM forms Cu-ATSM with copper, which is used for PET imaging to detect tumor hypoxia. ATSM is commonly used in coordination chemistry and radiopharmaceutical research .

HY-186094

(S,S)-Demethyl-reboxetine	Drug Derivative Drug Intermediate	Neurological Disease
(S,S)-Demethyl-reboxetine is a key phenolic precursor for the preparation of the PET tracer (S,S)-[ ¹¹C]-MeNER. (S,S)-Demethyl-reboxetine is also the demethylated derivative of Reboxetine (HY-14560). Efficient synthesis of the norepinephrine transporter (NET)-targeted tracer is achieved through ¹¹C methylation of (S,S)-Demethyl-reboxetine. (S,S)-Demethyl-reboxetine serves as a core raw material for the synthesis of radiopharmaceuticals related to NET imaging .

HY-402737

FTC-146 precursor	Drug Intermediate	Others
FTC-146 precursor (Compound s6) is a drug intermediate that can be used to prepare σ-1 receptor positron emission tomography tracers ([¹⁸F]FTC-146) .

HY-178221

(S)-P-SCN-BN-NOTA	Drug Intermediate	Cancer
(S)-P-SCN-BN-NOTA is a bifunctional chelating agent that can covalently link the radioactive nuclide ⁶⁴Cu with the ZPDGFRβ affibody, thereby constructing a molecular probe [⁶⁴Cu]Cu-NOTA-ZPDGFRβ for positron emission tomography .

HY-153709

Zalsenertant tetraxetan IPN-01087	Neurokinin Receptor	Cancer
Zalsenertant tetraxetan (IPN-01087) is a DOTA-conjugated antagonist of the neurohypophyseal hormone receptor subtype 1 (NTSR1). Zalsenertant tetraxetan is labeled with the radioactive isotope Lu-177 (177Lu), which can be used for molecular imaging to identify potential responders. Zalsenertant tetraxetan can be used in the radiotherapy research of solid tumors .

Cat. No.	Product Name	Type

HY-W102590

DOTMP	Biochemical Assay Reagents
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-B1684

Mebrofenin SQ 26962	Biochemical Assay Reagents
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

HY-W004649

Tris-BOC-cyclen	Biochemical Assay Reagents
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W109978

Tetrabutylammonium perrhenate	Biochemical Assay Reagents
Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.

Tetrabutylammonium perrhenate

Biochemical Assay Reagents

Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.

HY-W402032

Bis-Cbz-cyclen	Biochemical Assay Reagents
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-B1684R

Mebrofenin (Standard) SQ 26962 (Standard)	Biochemical Assay Reagents
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

Mebrofenin (Standard)

SQ 26962 (Standard)

Biochemical Assay Reagents

Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

Cat. No.	Product Name	Target	Research Area

HY-P10369

Betiatide	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Cardiovascular Disease Inflammation/Immunology
Betiatide, as a chelating agent for Technetium-99m ( ^99mTc), is used to prepare ^99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi . Betiatide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P11088

VCAM1 binding peptide	Transmembrane Glycoprotein Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology
VCAM1 binding peptide is a VCAM1 binder with internalization activity. VCAM1 binding peptide can be labeled with 5-FAM. VCAM1 binding peptide serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide is applicable to studies related to atherosclerosis .

HY-159771

FAP6-19	FAP	Cancer
FAP6-19 is a fibroblast activation protein (FAP) targeting radioligand with a K_d of 18.2 nM. FAP6-19 selectively delivers therapeutic radioactive nuclides (such as 177Lu) to the tumor site by targeting the overexpressed FAP protein in the tumor microenvironment, achieving precise killing of cancer cells while minimizing radiation damage to healthy tissues. FAP6-19 exhibits extremely high total cellular uptake and good intracellular retention ability in HT1080 cells. After being labeled with 111In, FAP6-19 produced extremely high tumor/kidney and tumor/liver dose ratios in the mouse model with 4T1 tumors. FAP6-19 can be used in the research of solid tumors expressing FAP.

9-cis-Retinal (Standard)	Structural Classification Terpenoids Diterpenoids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Organoid
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

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