2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Transmembrane Glycoprotein Radionuclide-Drug Conjugates (RDCs)
  4. VCAM1 binding peptide

VCAM1 binding peptide is a VCAM1 binder with internalization activity. VCAM1 binding peptide can be labeled with 5-FAM. VCAM1 binding peptide serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide is applicable to studies related to atherosclerosis.

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VCAM1 binding peptide

VCAM1 binding peptide Chemical Structure

CAS No. : 1311293-04-5

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VCAM1 binding peptide Related Antibodies

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Description

VCAM1 binding peptide is a VCAM1 binder with internalization activity. VCAM1 binding peptide can be labeled with 5-FAM. VCAM1 binding peptide serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide is applicable to studies related to atherosclerosis[1][2].

IC50 & Target[1]

RDC Peptide

 

In Vitro

The binding intensity of 5FAM-labeled VCAM1-binding peptide (10 mM; 4 h) to TNFα-treated HUVEC is higher than that to control HUVEC[1].
68Ga-MacroP (a VCAM1-binding peptide conjugate) binds specifically to VCAM-1 on the surface of TNF-α-stimulated HUVECs, and the activated cellular radioactive uptake is 4-fold higher than that of unstimulated control cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

VCAM1 binding peptide Related Antibodies
Molecular Weight

1390.57

Formula

C57H95N23O16S
CAS No.
Sequence

Val-His-Pro-Lys-Gln-His-Arg-Gly-Gly-Ser-Lys-Gly-Cys
Sequence Shortening

VHPKQHRGGSKGC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VCAM1 binding peptide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VCAM1 binding peptide1311293-04-5Transmembrane GlycoproteinRadionuclide-Drug Conjugates (RDCs)lysosomesendocytic pathwayNAMatherosclerosisquantum dotsTNFα-treated HUVECsVCAM1HUVECsPET radiopharmaceuticalsMMA-DOTAInhibitorinhibitorinhibit

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VCAM1 binding peptide
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