1. Biochemical Assay Reagents
  2. Mebrofenin

Mebrofenin (Synonyms: SQ 26962)

Cat. No.: HY-B1684
Handling Instructions

Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function.

For research use only. We do not sell to patients.

Mebrofenin Chemical Structure

Mebrofenin Chemical Structure

CAS No. : 78266-06-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
25 mg USD 90 In-stock
Estimated Time of Arrival: December 31
50 mg USD 150 In-stock
Estimated Time of Arrival: December 31
100 mg USD 250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function[1][2].

In Vitro

Tc-99m Mebrofenin is a 99mTc-labeled iminodiacetic (IDA) derivate, originally used for the diagnosis of a multitude of biliary diseases and, since recently, for the assessment of liver function[3].

Molecular Weight

387.23

Formula

C₁₅H₁₉BrN₂O₅

CAS No.

78266-06-5

SMILES

O=C(O)CN(CC(NC1=C(C)C=C(C)C(Br)=C1C)=O)CC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (645.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5824 mL 12.9122 mL 25.8244 mL
5 mM 0.5165 mL 2.5824 mL 5.1649 mL
10 mM 0.2582 mL 1.2912 mL 2.5824 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.37 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.37 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.37 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

MebrofeninSQ 26962SQ26962SQ-26962OtherssupplierliverfunctionhepaticextractionbloodclearanceiminodiaceticacidTc-99mdiagnosticInhibitorinhibitorinhibit

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Mebrofenin
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HY-B1684
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