267 Results for "

Sesquiterpenoid

" in MedChemExpress (MCE) Product Catalog:
Products (267)

267 Results for "Sesquiterpenoid" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-N0104
CAS No.: 4871-97-0
Synonyms: (-)-Curcumol
Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .
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3
3 Cited Publications
Cat. No.: HY-N0202
CAS No.: 73069-14-4
Synonyms: Asterolide
Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .
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2
2 Cited Publications
Cat. No.: HY-N0353
CAS No.: 13657-68-6
Synonyms: (+)-Curdione
Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression .
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1
1 Cited Publications
Cat. No.: HY-121262
CAS No.: 495-62-5
Synonyms: Bisabolene; γ-Bisabolene
Bisabolene (mixture of isomers) (Bisabolene) is a sesquiterpenoid plant natural product and also a hydrocarbon precursor for various industry-relevant chemicals. Bisabolene (mixture of isomers) serves as an important precursor for the production of industry-relevant chemicals such as biofuels, bioplastics, pharmaceuticals and cosmetics .
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1 Cited Publications
Cat. No.: HY-N10014
CAS No.: 22451-73-6
Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC50 value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .
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1
1 Cited Publications
Cat. No.: HY-103524
CAS No.: 3569-10-6
Purity:  ≥99.0%
Synonyms: (-)-Valerenic Acid
Research Areas:  

Neurological Disease

Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties .
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1
1 Cited Publications
Cat. No.: HY-N8284
CAS No.: 33649-15-9
Tomentosin is an orally active natural sesquiterpenoid lactone. Tomentosin exhibits multiple activities such as anti-tumor, anti-fungal, anti-inflammatory, anti-oxidant and neuroprotective effects. Tomentosin can inhibit tumor cell proliferation, migration and invasion, and induce apoptosis. Tomentosin can be used in the research of tumors, inflammation and nervous system diseases .
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1
1 Cited Publications
Cat. No.: HY-N3980
CAS No.: 489-86-1
Synonyms: Champacol; Guaiac alcohol
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
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Cat. No.: HY-N12804
CAS No.: 19435-97-3
Synonyms: (-)-Torreyol
δ-Cadinol ((-)-Torreyol) is a sesquiterpenoid compound and fungicide produced by the basidiomycete Boreostereum vibrans. δ-Cadinol is used for the research of fungal infections .
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Cat. No.: HY-N3340
CAS No.: 179388-54-6
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC50 value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .
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Cat. No.: HY-N8736
CAS No.: 28593-90-0
Eicosanyl (E)-caffeate is a sesquiterpenoid isolated from the root of Wikstroemia scytophylla .
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Cat. No.: HY-N10321
CAS No.: 117634-64-7
Kanshone C is a sesquiterpenoid of Nardostachys chinensis roots .
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Cat. No.: HY-N3337
CAS No.: 327601-97-8
Macrocarpal L is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus .
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Cat. No.: HY-126484
CAS No.: 60048-73-9
Target:  

Fungal

Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .
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Cat. No.: HY-N1571
CAS No.: 34169-70-5
Pterosin D is a sesquiterpenoid, that can be isolated from aerial plants of P. cretica .
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Cat. No.: HY-119735
CAS No.: 17015-43-9
Target:  

Others

Research Areas:  

Cardiovascular Disease

Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .
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Cat. No.: HY-N8934
CAS No.: 1232676-22-0
6β-Hydroxytomentosin, a sesquiterpenoid, can be found in flowers of Inula japonica. 6β-Hydroxytomentosin exhibits weak cytotoxicities against A549, SK-OV-3, HepG-2 and HT-29 cell lines .
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Cat. No.: HY-N16123
CAS No.: 73215-91-5
Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research .
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Cat. No.: HY-N10623
CAS No.: 2767066-84-0
5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells .
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Cat. No.: HY-134572
CAS No.: 35938-43-3
(2S,3S)-Pterosin C is a natural sesquiterpenoid compound .
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