26 Results for "

Sonic

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Sonic" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100515
CAS No.: 1132653-79-2
Purity:  99.42%
Target:  

Hedgehog

Research Areas:  

Inflammation/Immunology

Robotnikinin is a small molecule capable of binding to and inhibiting the activity of Sonic Hedgehog (Shh) signaling up stream of Smo .
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3
3 Cited Publications
Cat. No.: HY-P7409
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (Drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-B0508
CAS No.: 16773-42-5
Synonyms: Ro 7-0207
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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2
2 Cited Publications
Cat. No.: HY-P70467
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (Drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-158059
Purity:  99.60%
Target:  

Hedgehog

Research Areas:  

Cancer

DS-1-38 is an EYA1 antagonist that blocks Sonic Hedgehog (SHH) signaling. EYA1 is a haloacid dehalogenase phosphatase and transcription factor that regulates tumorigenesis and proliferation in SHH medulloblastoma (SHH-MB) .
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1
1 Cited Publications
Cat. No.: HY-P73418
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (Drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P10875
CAS No.: 2130846-15-8
Target:  

Hedgehog

Research Areas:  

Cancer

HL2-m5 is the inhibitor for the interaction between sonic hedgehog/patched (Shh/PTCH1) with Kd of 170 nM for Shh. HL2-m5 inhibits activation of Hedgehog signaling pathway and transcription of Gli-controlled gene with an IC50 of 230 nM .
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Cat. No.: HY-B0508S1
Synonyms: Ro 7-0207-13C2,15N2
Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-147743
CAS No.: 1126365-66-9
Target:  

Smo

Research Areas:  

Cancer

SMO-IN-1 (Compound 15) is an orally active Smoothened (SMO) inhibitor with an EC50 of 89 nM against sonic Hh protein (shh) .
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Cat. No.: HY-147744
CAS No.: 1126366-28-6
Target:  

Smo

Research Areas:  

Cancer

AZD7254 is an orally active Smoothened (SMO) inhibitor with an EC50 of 1.0 nM against sonic Hh protein (shh) .
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Cat. No.: HY-162135
CAS No.: 3032026-05-1
MAT2A-IN-14 (compound H3) is a MAT2A inhibitor, and generates reactive oxygen species after sonication to specifically degrade cellular MAT2A via rapid oxidative reactions. Combination of MAT2A-IN-14 and sonication induces 87% MAT2A depletion in human colon cancer cell .
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Cat. No.: HY-120664
CAS No.: 1314295-24-3
Target:  

Hedgehog

Research Areas:  

Cancer

BRD50837 is a potent inhibitor of Sonic Hedgehog (Shh), with the EC50 of 0.09 μM. BRD50837 plays an important role in cancer research .
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Cat. No.: HY-N16232
CAS No.: 3091880-01-9
Synonyms: 2-α-Carboxy cholestanol
Category:  

Lipids

Target:  

Hedgehog

2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC50 of ~5 μM.
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Cat. No.: HY-116455
CAS No.: 1446352-30-2
Target:  

Fluorescent Dye

Research Areas:  

Cancer

BRD-9526 is a potent and selective Sonic Hedgehog (Shh) pathway inhibitor with potential anti-cancer activity. The mechanism of BRD-9526 is similar in some ways to commonly used inhibitors such as cyclopamine, but is significantly different in other ways. The discovery of BRD-9526 may provide a useful probe for studying complex signaling pathways .
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Cat. No.: HY-B0508S
CAS No.: 2747915-64-4
Synonyms: Ro 7-0207-d5
Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-B0508R
CAS No.: 16773-42-5
Synonyms: Ro 7-0207 (Standard)
Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-P81157
Synonyms: Sonic hedgehog; Vhh-1; Sonic hedgehog protein; SHH; HHG 1; HHG1; HLP 3; HLP3; Holoprosencephaly 3; HPE 3; HPE3; MCOPCB5; SMMC I; SMMCI; Sonic Hedgehog (Drosophila) homolog; Sonic hedgehog homolog (Drosophila); Sonic hedgehog homolog; Sonic hedgehog protein; TPT; TPTPS; Sonic hedgehog protein N-product; SHH_HUMAN.

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P73417
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (Drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT; Sonic Hedgehog Signaling Molecule; SHH Signaling Molecule
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7288
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (Drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:  
Mouse
Source:  
CHO
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Cat. No.: HY-P7290
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (Drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:  
Mouse
Source:  
E. coli
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