324 Results for "

T-lymphocyte

" in MedChemExpress (MCE) Product Catalog:
Products (324)

324 Results for "T-lymphocyte" in MCE Product Catalog:

106
106 Publications Verification
Cat. No.: HY-13756
CAS No.: 104987-11-3
Purity:  99.93%
Synonyms: FK506; Fujimycin; FR900506
Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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106
106 Publications Verification
Cat. No.: HY-13756A
CAS No.: 109581-93-3
Purity:  99.67%
Synonyms: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate
Tacrolimus (FK506) monohydrate, a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus monohydrate inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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13
13 Cited Publications
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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12
12 Cited Publications
Cat. No.: HY-P70527
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Human
Source:  
HEK293
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9
9 Cited Publications
Cat. No.: HY-104037
CAS No.: 2055536-64-4
Purity:  99.14%
Synonyms: LYC-55716
Target:  

ROR

Research Areas:  

Cancer

Cintirorgon (LYC-55716) is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival .
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6
6 Cited Publications
Cat. No.: HY-P7036
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P9901
CAS No.: 477202-00-9
Synonyms: MDX-010; BMS-734016

Target:  

CTLA-4

Research Areas:  

Cancer

Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies .
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5
5 Cited Publications
Cat. No.: HY-P70753
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Mouse
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-P80609
Synonyms: CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Rat

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3
3 Cited Publications
Cat. No.: HY-P1569
CAS No.: 151705-84-9
Synonyms: LCMV GP(33-41) M-peptide; gp33 epitope
Target:  

Arenavirus

Research Areas:  

Infection Inflammation/Immunology

LCMV gp33-41, the carboxyl-extended 9-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
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3
3 Cited Publications
Cat. No.: HY-P1569A
Synonyms: LCMV GP(33-41) M-peptide TFA; gp33 epitope TFA
Target:  

Arenavirus

Research Areas:  

Inflammation/Immunology

LCMV gp33-41 (TFA), the carboxyl-extended 9-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
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3
3 Cited Publications
Cat. No.: HY-P79326
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Rat
Source:  
CHO
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3
3 Cited Publications
Cat. No.: HY-P700194AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Mouse
Source:  
E. coli
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3
3 Cited Publications
Cat. No.: HY-N0591
CAS No.: 477-43-0
Synonyms: (-)-Dehydrocostus lactone; Epiligulyl oxide
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) is a natural sesquiterpene that can be isolated from Saussurea lappa. Dehydrocostus Lactone has multiple activities such as anti-inflammatory, antibacterial, anti-tumor, and immunomodulatory effects. Dehydrocostus Lactone has an MIC of 2 µg/mL against Mycobacterium tuberculosis. Dehydrocostus Lactone can also inhibit the killing activity of cytotoxic T lymphocytes and induce apoptosis in tumor cells .
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3
3 Cited Publications
Cat. No.: HY-P99052
CAS No.: 1858168-59-8
Synonyms: BGB-A317

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma .
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2
2 Cited Publications
Cat. No.: HY-100731
CAS No.: 79217-60-0
Purity:  99.31%
Target:  

Cyclophilin

Research Areas:  

Inflammation/Immunology Cancer

Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes .
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2
2 Cited Publications
Cat. No.: HY-P76377
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GZMA; Cytotoxic T-lymphocyte Proteinase 1; Prev. CTLA3; Granzyme 1; Prev. HFSP; H Factor; CTL Tryptase; HF; Fragmentin-1; Granzyme A (Cytotoxic T-lymphocyte-Associated Serine Esterase-3; Hanukah Factor Serine Protease); Granzyme A (Granzyme 1, Cytotoxic T
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P7372
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Mouse
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P7373
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-lymphocyte-Associated Protein 8; Prev. CTLA8; Interleukin-17A; Prev. IL17; CTLA-8; IL-17A; Interleukin-17; IL-17; ILA17; Interleukin 17 (Cytotoxic T-lymphocyte-Associated Serine Esterase 8); Interleukin 17A; Cytotoxic T-lymphocyte-Assoc
Species:  
Human
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-N6939
CAS No.: 82508-31-4
Pseudolaric Acid B is an orally active diterpene acid. Pseudolaric Acid B has anti-fungal, anti-fertility, anti-angiogenesis and anticancer activity, and can induce tumor cell apoptosis and autophagy. In addition, Pseudolaric Acid B can inhibit the secretion of hepatitis B virus (HBV) and has immunosuppressive effect, selectively inhibiting the proliferation of T lymphocytes and the production of IL-2 .
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