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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
Trt
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "Trt" in MCE Product Catalog:
1
1 Cited Publications
Art. -Nr.: HY-W010712
CAS. Nr.: 109425-51-6
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1
1 Cited Publications
Art. -Nr.: HY-W013081
CAS. Nr.: 132327-80-1
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1 Cited Publications
Art. -Nr.: HY-W010788
CAS. Nr.: 32926-43-5
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Art. -Nr.: HY-W007798
CAS. Nr.: 103213-32-7
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Art. -Nr.: HY-W002327
CAS. Nr.: 132388-59-1
Art. -Nr.: HY-W010714
CAS. Nr.: 200623-62-7
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Art. -Nr.: HY-W008876
CAS. Nr.: 201531-88-6
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Art. -Nr.: HY-W010734
CAS. Nr.: 111061-56-4
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Art. -Nr.: HY-W013155
CAS. Nr.: 35146-32-8
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Art. -Nr.: HY-W010724
CAS. Nr.: 167015-11-4
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Art. -Nr.: HY-173374
CAS. Nr.: 3114056-16-2
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DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors .
Art. -Nr.: HY-W142161
CAS. Nr.: 1217840-61-3
Synonyms: Fmoc-MeHis(Trt)-OH
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Art. -Nr.: HY-W011156
CAS. Nr.: 27144-18-9
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Mpa(Trt) is a linker and thiol handle for tert-Boc solid phase peptide synthesis .
Art. -Nr.: HY-W048697
CAS. Nr.: 201532-01-6
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Phe-Lys(Trt)-PAB is a cathepsin B substrate, and a cleavable ADC linker. Phe-Lys(Trt)-PAB acts as a lysosomally cleavable substrate for cysteine protease cathepsin B, with cleavage enabling linked anticancer drug release via self-immolative spacer . Phe-Lys(Trt)-PAB can be used for synthesis of ADCs .
Art. -Nr.: HY-W053550
CAS. Nr.: 25840-82-8
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Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Art. -Nr.: HY-W108518
CAS. Nr.: 2061897-68-3
Synonyms: Boc-his(Trt)-aib-oh
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(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds.
Art. -Nr.: HY-W010719
CAS. Nr.: 180570-71-2
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Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
