2 Results for "

UACC-257 cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "UACC-257 cells" in MCE Product Catalog:

Cat. No.: HY-110172
CAS No.: 1461648-55-4
Target:  

PDI

Research Areas:  

Cancer

PDI-IN-1 is a cell-permeable PDI covalent inhibitor with an IC50 of 1.7 μM against bovine PDI. PDI-IN-1 specifically modifies the Cys397 residue at the active site of human PDI, selectively labels endogenous PDI in living mammalian cancer cells, and effectively inhibits PDI-mediated insulin aggregation in vitro. PDI-IN-1 exhibits significant anti-tumor activity and inhibits the growth of various cancer cell lines .
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Cat. No.: HY-P991964
Synonyms: Rendomab-B49

Target:  

Endothelin Receptor

Research Areas:  

Cancer

Rendomab B4 (Rendomab-B49) is a monoclonal antibody targeting ETB. Rendomab B4 preferentially binds to ETB in the active conformational state and exhibits selectivity for ETB on melanoma cells. Rendomab B4 inhibits the G protein-dependent phospholipase C (PLC) pathway, blocks ET-3-induced Gαi/o-mediated inhibition of adenylate cyclase, and does not affect the activation of the ERK1/2 pathway. Rendomab B4 is applicable to melanoma-related research .
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