1 Result for "

USP1-IN-20

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "USP1-IN-20" in MCE Product Catalog:

Cat. No.: HY-189455
CAS No.: 3094127-54-2
Research Areas:  

Cancer

USP1-IN-20 is an orally effective and selective USP1 inhibitor with an IC50 of 3.0 nM. USP1-IN-20 inhibits the USP1-UAF1 complex, leading to the accumulation of Ub-PCNA, which in turn induces DNA damage and G2/M phase arrest, while simultaneously promoting the degradation of the oncogenic protein c-MYC. USP1-IN-20 can be used for research on breast cancer and diffuse large B-cell lymphoma .
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