2 Results for "

Vasodepressor effect

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Vasodepressor effect" in MCE Product Catalog:

3
Cotinine
Cotinine
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3 Cited Publications
Cat. No.: HY-B1178
CAS No.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Category:  

Alkaloids Pyrrole Alkaloids Nicotiana tabacum L. Other Diseases Pyridine Alkaloids Plants Solanaceae Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite nAChR

Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
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Cotinine (Standard)
Cotinine (Standard)
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Cat. No.: HY-B1178R
CAS No.: 486-56-6
Synonyms: (-)-Cotinine (Standard); (S)-Cotinine (Standard); NIH-10498 (Standard)
Category:  

Alkaloids Pyrrole Alkaloids Nicotiana tabacum L. Pyridine Alkaloids Plants Solanaceae Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite nAChR

Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
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