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Vasopressin Receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Vasopressin Receptor (82) 5-HT Receptor (1) Adenylate Cyclase (2) Adrenergic Receptor (3) Angiotensin Receptor (1) Apoptosis (2) Arrestin (1) Autophagy (3) Dopamine Receptor (1) Drug Metabolite (1) Endogenous Metabolite (5) Isotope-Labeled Compounds (5) mAChR (3) Opioid Receptor (2) Oxytocin Receptor (19) P-glycoprotein (1) PTHR (1) Reference Standards (13)
By Research Areas:	Cancer (15) Cardiovascular Disease (52) Endocrinology (44) Inflammation/Immunology (5) Metabolic Disease (15) Neurological Disease (32)

105

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Vasopressin Receptor Neuropeptide S Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1811

Vasopressin 5+ Cited Publications Arginine Vasopressin; Antidiuretic hormone	Endogenous Metabolite	Neurological Disease
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-17000

Tolvaptan Maximum Cited Publications 19 Publications Verification OPC-41061	Vasopressin Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V₂R) antagonist with an IC₅₀ of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia .

HY-P0049

Argipressin Maximum Cited Publications 10 Publications Verification Arg8-Vasopressin; AVP	Vasopressin Receptor	Neurological Disease Cancer
Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.

HY-18347A

Conivaptan hydrochloride 10+ Cited Publications YM 087	Vasopressin Receptor	Cardiovascular Disease Endocrinology
Conivaptan (hydrochloride) is a non-peptide antagonist of **vasopressin receptor, with K_i** values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.

HY-17572

Atosiban 5+ Cited Publications RW22164; RWJ22164	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-119706

Barbadin 15+ Cited Publications	Apoptosis Arrestin	Others
Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC₅₀ values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis .

HY-10066

Nelivaptan 1 Publications Verification SSR-149415	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
Nelivaptan (SSR-149415) is a selective and orally active **vasopressin V_1b receptor antagonist (K_i*: 3.7 and 1.3 nM for native and recombinant rat V_1b receptors, respectively). Nelivaptan inhibits arginine vasopressin* (AVP)-induced Ca ²⁺ increase and corticotropin secretion. Nelivaptan can be used for research of stress, anxiety and depression .

HY-14185

Lixivaptan 4 Publications Verification VPA-985; WAY-VPA 985	Vasopressin Receptor	Cardiovascular Disease Endocrinology
Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective **vasopressin receptor V2 antagonist, with IC₅₀** values of 1.2 and 2.3 nM for human and rat V2, respectively.

HY-15522

WAY-267464 2 Publications Verification	Oxytocin Receptor	Neurological Disease
WAY-267464 is a non-peptide *oxytocin receptor* (OTR)** agonist. WAY-267464 can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder .

HY-109024

Balovaptan RG7314	Vasopressin Receptor	Cardiovascular Disease Neurological Disease Endocrinology
Balovaptan (RG7314) is an orally available, selective brain-penetrant **vasopressin 1a (hV1a) receptor antagonist, with K_i*s of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors*, and is used for the research of autism.

HY-105239

Selepressin FE 202158	Vasopressin Receptor	Cardiovascular Disease
Selepressin (FE 202158) is a selective **vasopressin V_1A receptor** agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock .

HY-W539944

Argipressin acetate Maximum Cited Publications 10 Publications Verification Arg8-Vasopressin acetate; AVP acetate	Vasopressin Receptor Apoptosis	Neurological Disease Cancer
Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .

HY-15009

Fuscoside 1 Publications Verification OPC-21268	Vasopressin Receptor	Cardiovascular Disease Endocrinology
Fuscoside (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC₅₀ of 0.4 μM.

HY-18346

Mozavaptan 1 Publications Verification OPC-31260	Vasopressin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology Cancer
Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active **vasopressin V₂ receptor antagonist with an IC₅₀** of 14 nM. Mozavaptan shows ~85-fold selectivity for V₂ receptor over V₁ receptor (IC₅₀ of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment .

HY-12554

Terlipressin	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin is a vasopressin analogue with potent vasoactive properties. Terlipressin is a highly selective **vasopressin V1 receptor** agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin exerts anti-inflammatory and anti-oxidative effects. Terlipressin has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-15010

L-371,257 1 Publications Verification	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology
L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (K_i=19 nM) and **vasopressin V1a receptor (K_i**=3.7 nM) .

HY-17572A

Atosiban acetate 5+ Cited Publications RW22164 acetate; RWJ22164 acetate	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-B0662

Imidafenacin KRP-197; ONO-8025	mAChR Vasopressin Receptor	Neurological Disease Endocrinology
Imidafenacin (KRP-197; ONO-8025) is an orally active inhibitor of muscarinic (mAChR) M₁ and M₃ receptors. Imidafenacin potently inhibits bladder contraction in vivo and exerts an antidiuretic effect by enhancing the signaling pathway of vasopressin (antidiuretic hormone). Imidafenacin can be used in research related to overactive bladder .

HY-19381

WAY-151932 VNA-932; WAY-VNA 932	Vasopressin Receptor	Metabolic Disease Endocrinology
WAY-151932 is a **vasopressin V₂-receptor agonist with IC₅₀** of 80.3 nM and 778 nM in human-V₂ binding and V_1a binding assay.

HY-12554A

Terlipressin diacetate 2 Publications Verification	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective **vasopressin V1 receptor** agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-P0004

Lysipressin 2 Publications Verification Lysine Vasopressin; [Lys8]-Vasopressin	Adenylate Cyclase Oxytocin Receptor	Cardiovascular Disease Neurological Disease
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-P0083

Ornipressin POR-8	Vasopressin Receptor	Cardiovascular Disease
Ornipressin (POR-8) is a *vasopressin* agonist specific for the V1 receptor. Ornipressin can be used as a local vasoconstrictor. Ornipressin can reverse the hypotension associated with combine general/epidural anesthesia. Ornipressin has antidiuretic activity. Ornipressin decreases renal vascular resistance and increases renal blood flow in renal failure model .

HY-105239A

Selepressin acetate FE 202158 acetate	Vasopressin Receptor	Cardiovascular Disease
Selepressin (FE 202158) acetate is a selective **vasopressin V_1A receptor** agonist. Selepressin acetate is a potent vasopressin. Selepressin acetate can be used in the study of septic shock.

HY-123593

Mozavaptan hydrochloride 1 Publications Verification OPC-31260 hydrochloride	Vasopressin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology Cancer
Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine derivative and a potent, selective, competitive and orally active **vasopressin V₂ receptor antagonist with an IC₅₀** of 14 nM. Mozavaptan hydrochloride shows ~85-fold selectivity for V₂ receptor over V₁ receptor (IC₅₀ of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan hydrochloride has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment .

HY-14887

Fedovapagon 1 Publications Verification VA106483	Vasopressin Receptor	Metabolic Disease
Fedovapagon (VA106483) is a selective and orally active vasopressin V2 receptor (V2R) agonist with an EC₅₀ of 24 nM. Fedovapagon can be used in the research of nocturia .

HY-P5535

Invopressin OCE-205	Vasopressin Receptor	Inflammation/Immunology
Invopressin (Compound 42) is a **vasopressin V1A receptor partial agonist (EC₅₀**: 1.0 nM). Invopressin can be used for research of cirrhosis, including bacterial peritonitis, HRS2 and refractory ascites .

HY-108679

WAY-267464 hydrochloride 2 Publications Verification	Oxytocin Receptor	Neurological Disease
WAY-267464 (hydrochloride) is a non-peptide *oxytocin receptor* (OTR)** agonist. WAY-267464 (hydrochloride) can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 (hydrochloride) can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder .

HY-14778

Retosiban GSK 221149; GSK 221149A	Oxytocin Receptor	Neurological Disease Endocrinology
Retosiban (GSK221149A) is a potent, selective, and orally active oxytocin receptor antagonist (K_i (hOT) = 0.65 nM, K_i (rOT) = 4.1 nM) with no detectable agonist activity. Retosiban has nanomolar affinity for the oxytocin receptor with >1400-fold selectivity over the closely related vasopressin receptors. Retosiban inhibits spontaneous and induces uterine contractions. Retosiban can be studied in research for preterm labour .

HY-105685

SRX246	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
SRX246 is a potent, BBB-penetrant, highly selective **vasopressin 1a (V1a) receptor antagonist (K_i*=0.3 nM for human V1a). SRX246 has no interaction at V1b and V2 receptors. SRX246 also displays negligible binding at 64 others receptors* classes, including 35 G-proteincoupled receptors. SRX246 can be used for treatment of stress-related disorders .

HY-117820

TASP0390325	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
TASP0390325 is a high affinity and orally active *arginine vasopressin* receptor 1B** (V1B receptor) antagonist with antidepressant and anxiolytic activities .

HY-B1811AS1

Vasopressin-d5 TFA Arginine Vasopressin-d5 TFA; Antidiuretic hormone-d5 TFA	Isotope-Labeled Compounds	Neurological Disease
Vasopressin-d5 TFA is the TFA salt form of Vasopressin-d5 (HY-B1811S1). Vasopressin-d5 TFA is an isotope-labeled compound of Vasopressin (HY-B1811). Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-12981

RG7713 2 Publications Verification RO5028442	Vasopressin Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
RG7713 (RO5028442) is a highly potent, selective and brain-penetrant Vasopressin 1a (V1a) receptor antagonist with K_is of 1 nM (hV1a) and 39 nM (mV1a).

HY-P1390

d[Cha4]-AVP	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP is a potent and selective **vasopressin (AVP) V1b receptor agonist with a K_i** of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-108678

TC OT 39	Oxytocin Receptor Vasopressin Receptor	Neurological Disease
TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC₅₀=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an K_i value of 330 nM. TC OT 39 exhibits sedative effects in mouse models .

HY-116567

OPC-51803	Vasopressin Receptor	Metabolic Disease
OPC-51803 is an orally active nonpeptide vasopressin V₂ receptor agonist. OPC-51803 can be used for the research of micturition disorders that result in frequent micturition, such as that from polyuria, nocturnal polyuria, and some kinds of urinary incontinence .

HY-P1163A

D[LEU4,LYS8]-VP TFA	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
D[LEU4,LYS8]-VP TFA is a selective agonist of **vasopressin V_1b receptor, with the K_is of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V_1b** receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities .

HY-136960

β2AR antagonist 1	Adrenergic Receptor	Others
β2AR antagonist 1 is a potent *β2-adrenergic receptor* (β2AR)** inhibitor. β2AR antagonist 1 exhibits high selectivity for β2AR over β1AR, vasopressin receptor type 2, and angiotensin type 1 receptor. β2AR antagonist 1 stabilizes the inactive conformation of β2AR and interferes with its coupling to G proteins and β-arrestins .

HY-18347

Conivaptan YM 087 free base	Vasopressin Receptor	Cardiovascular Disease
Conivaptan (YM 087 free base) is antagonist for **vasopressin V1A receptor and vasopressin V2 receptor**. Conivaptan ameliorates congestive heart failure, improves cardiac systolic function .

HY-146272

Vasopressin V2 receptor antagonist 1	Vasopressin Receptor	Endocrinology
Vasopressin V2 receptor antagonist 1 is a vasopressin V2 receptor (V₂R) antagonist with a K_i value of 3.8 nM. Vasopressin V2 receptor antagonist 1 inhibits renal cyst formation in embryonic renal cyst models and mouse models. Vasopressin V2 receptor antagonist 1 can be used in research related to autosomal dominant polycystic kidney disease .

HY-159507

Brezivaptan Brezivaptanum; TH1773; TS-121	Vasopressin Receptor	Endocrinology
Brezivaptan (Brezivaptanum; TH1773; TS-121) is a vasopressin receptor antagonist .

HY-19732

BIBS 39	Angiotensin Receptor	Cardiovascular Disease
BIBS 39 is a non-peptide angiotensin II receptor antagonist with antihypertensive activity, with higher affinity for the AT1 receptor than for the AT2 receptor. BIBS 39 competitively blocks AT1-mediated vasoconstriction and pressor responses, and effectively inhibits the activity of the renin-angiotensin-aldosterone system. BIBS 39 reduces diastolic blood pressure and induces mild, transient reflex tachycardia, with no off-target functional activity on the norepinephrine, K ⁺/Cl ⁻ or vasopressin pathways. BIBS 39 can be used in research related to hypertension and renal hypertension ^[1][2 ^][3].

HY-157220

Tolvaptan phosphate ester sodium	Vasopressin Receptor	Cardiovascular Disease
Tolvaptan phosphate ester sodium, a prodrug of Tolvaptan (HY-17000), can be used in the study of cardiac edema. Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation .

HY-P4010

Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin	Vasopressin Receptor	Others
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor .

HY-18344

Satavaptan SR 121463	Vasopressin Receptor	Metabolic Disease
Satavaptan (SR 121463) is an antagonist for **vasopressin V2 receptor*. Satavaptan regulates the vasopressin* regulated phosphopeptides and vasopressin-mediated signaling pathway. Satavaptan is potential in ameliorating hyponatremia .

HY-116567A

(S)-OPC-51803	Endogenous Metabolite	Endocrinology
(S)-OPC-51803 is an agonist of the vasopressin V2 receptor, with activity in suppressing nocturia and urinary incontinence. (S)-OPC-51803 was evaluated in terms of biological activity and showed a stronger V2 receptor agonist effect compared to its (R)-isomer. The use of (S)-OPC-51803 may improve the patient's ability to control nocturnal polyuria .

HY-162394

Vasopressin V2 receptor antagonist 2	Vasopressin Receptor	Metabolic Disease
Vasopressin V2 receptor antagonist 2 (Compound 33) is an antagonist of the arginine vasopressin V₂ receptor (V₂R) with a K_i value of 6.2 nM. Vasopressin V2 receptor antagonist 2 can effectively reduce cAMP levels, thereby inhibiting the growth of renal cysts[1].

HY-178573

V1b Receptor antagonist-1	Vasopressin Receptor	Neurological Disease
V1b receptor antagonist-1 is a potent, selective and brain-penetrant vasopressin 1b (V1b) receptor antagonist. V1b receptor antagonist-1 exhibits anti-depressant activity. V1b receptor antagonist-1 can be used for the research of neurological disease, such as depression .

HY-W752502

Docarpamine	Dopamine Receptor Vasopressin Receptor Adrenergic Receptor	Cardiovascular Disease
Docarpamine is an orally active dopamine prodrug that can be hydroxylated in the small intestine and liver to form active dopamine. Docarpamine mainly activates D1-like receptors in peripheral blood vessels to lower blood pressure and heart rate in a state of spontaneous hypertension. Docarpamine exerts a pressor and tachycardic effect by activating D1-like receptors, vasopressin V1 receptors, and α-adrenergic receptors in normal blood pressure conditions. Docarpamine can be used for research on renal vascular dilation and diuresis .

HY-P1162

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a **vasopressin V1 receptor** selective antagonist .

HY-B1811R

Vasopressin (Standard) Arginine Vasopressin (Standard); Antidiuretic hormone (Standard)	Endogenous Metabolite Reference Standards	Neurological Disease
Vasopressin (Standard) is the analytical standard of Vasopressin. This product is intended for research and analytical applications. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

Cat. No.	Product Name	Target	Research Area

HY-B1811

Vasopressin 5+ Cited Publications Arginine Vasopressin; Antidiuretic hormone	Endogenous Metabolite	Neurological Disease
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P0049

Argipressin Maximum Cited Publications 10 Publications Verification Arg8-Vasopressin; AVP	Vasopressin Receptor	Neurological Disease Cancer
Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.

HY-17572

Atosiban 5+ Cited Publications RW22164; RWJ22164	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-P1852

TIP 39, Tuberoinfundibular Neuropeptide 1 Publications Verification	Adenylate Cyclase PTHR	Neurological Disease
TIP 39, Tuberoinfundibular Neuropeptide is an endogenous PTH2 receptor agonist and antihypertensive agent. TIP 39, Tuberoinfundibular Neuropeptide selectively activates the PTH2 receptor with no activity on the PTH1 receptor, stimulates cAMP production, activates adenylate cyclase, and elevates intracellular calcium levels via mobilization from intracellular stores. TIP 39, Tuberoinfundibular Neuropeptide is highly conserved in humans, mice, and rats. TIP 39, Tuberoinfundibular Neuropeptide is applicable to research related to nociception and inflammation-induced pain .

HY-105239

Selepressin FE 202158	Vasopressin Receptor	Cardiovascular Disease
Selepressin (FE 202158) is a selective **vasopressin V_1A receptor** agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock .

HY-W539944

Argipressin acetate Maximum Cited Publications 10 Publications Verification Arg8-Vasopressin acetate; AVP acetate	Vasopressin Receptor Apoptosis	Neurological Disease Cancer
Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .

HY-17572A

Atosiban acetate 5+ Cited Publications RW22164 acetate; RWJ22164 acetate	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-12554A

Terlipressin diacetate 2 Publications Verification	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective **vasopressin V1 receptor** agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-P0004

Lysipressin 2 Publications Verification Lysine Vasopressin; [Lys8]-Vasopressin	Adenylate Cyclase Oxytocin Receptor	Cardiovascular Disease Neurological Disease
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-P0083

Ornipressin POR-8	Vasopressin Receptor	Cardiovascular Disease
Ornipressin (POR-8) is a *vasopressin* agonist specific for the V1 receptor. Ornipressin can be used as a local vasoconstrictor. Ornipressin can reverse the hypotension associated with combine general/epidural anesthesia. Ornipressin has antidiuretic activity. Ornipressin decreases renal vascular resistance and increases renal blood flow in renal failure model .

HY-105239A

Selepressin acetate FE 202158 acetate	Vasopressin Receptor	Cardiovascular Disease
Selepressin (FE 202158) acetate is a selective **vasopressin V_1A receptor** agonist. Selepressin acetate is a potent vasopressin. Selepressin acetate can be used in the study of septic shock.

HY-P5535

Invopressin OCE-205	Vasopressin Receptor	Inflammation/Immunology
Invopressin (Compound 42) is a **vasopressin V1A receptor partial agonist (EC₅₀**: 1.0 nM). Invopressin can be used for research of cirrhosis, including bacterial peritonitis, HRS2 and refractory ascites .

HY-P1390

d[Cha4]-AVP	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP is a potent and selective **vasopressin (AVP) V1b receptor agonist with a K_i** of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P1163A

D[LEU4,LYS8]-VP TFA	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
D[LEU4,LYS8]-VP TFA is a selective agonist of **vasopressin V_1b receptor, with the K_is of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V_1b** receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities .

HY-P0083A

Ornipressin acetate POR-8 acetate	Vasopressin Receptor	Cardiovascular Disease
Ornipressin (POR-8) acetate is a potent vasoconstrictor, hemostatic and renal agent. Ornipressin acetate is a *vasopressin* agonist specific for the V1 receptor. Ornipressin acetate can be used as a local vasoconstrictor. Ornipressin acetate can reverse the hypotension associated with combine general/epidural anesthesia. Ornipressin acetate has antidiuretic activity. Ornipressin acetate decreases renal vascular resistance and increases renal blood flow in renal failure model .

HY-P4010

Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin	Vasopressin Receptor	Others
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor .

HY-162394

Vasopressin V2 receptor antagonist 2	Vasopressin Receptor	Metabolic Disease
Vasopressin V2 receptor antagonist 2 (Compound 33) is an antagonist of the arginine vasopressin V₂ receptor (V₂R) with a K_i value of 6.2 nM. Vasopressin V2 receptor antagonist 2 can effectively reduce cAMP levels, thereby inhibiting the growth of renal cysts[1].

HY-P1162

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a **vasopressin V1 receptor** selective antagonist .

HY-B1811R

Vasopressin (Standard) Arginine Vasopressin (Standard); Antidiuretic hormone (Standard)	Endogenous Metabolite Reference Standards	Neurological Disease
Vasopressin (Standard) is the analytical standard of Vasopressin. This product is intended for research and analytical applications. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P5213

Vasopressin Dimer (parallel) TFA	Vasopressin Receptor Oxytocin Receptor	Endocrinology
Vasopressin Dimer (parallel) TFA is a parallel dimer of Vasopressin (HY-B1811). Vasopressin Dimer (parallel) TFA can activate four G protein-coupled receptors, V1aR, V1bR, V2R, and OTR .

HY-P5006

(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin d(CH2)5[Tyr(Me)2, Dab5]AVP	Vasopressin Receptor	Cardiovascular Disease
(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin (d(CH2)5[Tyr(Me)2, Dab5]AVP) is a specific antagonist of **vasopressin V_1a receptor**, with a pA₂ of 6.71 .

HY-P1737

Conopressin S Con-S	Peptides	Cardiovascular Disease
Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a K_i of 8.3 nM .

HY-12554B

Terlipressin acetate	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective **vasopressin V1 receptor** agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-P1390A

d[Cha4]-AVP TFA	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP TFA is a potent and selective **vasopressin (AVP) V1b receptor agonist with a K_i** of 1.2 nM for human V1b receptor. d[Cha4]-AVP TFA shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P10325

Kalata B7	Vasopressin Receptor Oxytocin Receptor	Cardiovascular Disease
Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of oxytocin and vasopressin V_1a receptors .

HY-P1163

D[LEU4,LYS8]-VP	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
D[LEU4,LYS8]-VP is a selective agonist of **vasopressin V_1b receptor, with the K_is of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V_1b** receptor, respectively. D[LEU4,LYS8]-VP has weak antidiuretic, vasopressor, and in vitro oxytocic activities .

HY-P5010

(D-Arg8)-Inotocin	Vasopressin Receptor	Cardiovascular Disease
(D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V_1aR), with a K_i of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R .

HY-P3213

Dp[Tyr(methyl)2,Arg8]-Vasopressin	Vasopressin Receptor	Metabolic Disease
Dp[Tyr(methyl)2,Arg8]-Vasopressin is a non-selective peptide arginine vasopressin Vlb receptor antagonist .

HY-P5214

Vasopressin Dimer (anti-parallel) TFA	Vasopressin Receptor Oxytocin Receptor	Endocrinology
Vasopressin Dimer (anti-parallel) TFA is an anti-parallel dimer of Vasopressin (HY-B1811). Vasopressin Dimer (anti-parallel) TFA can activate four G protein-coupled receptors, V1aR, V1bR, V2R, and OTR .

HY-P4683A

(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin acetate	Vasopressin Receptor	Cardiovascular Disease
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats .

HY-P4683

(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin	Vasopressin Receptor	Cardiovascular Disease
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats .

HY-12554AR

Terlipressin diacetate (Standard)	Vasopressin Receptor Reference Standards	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin (diacetate) (Standard) is the analytical standard of Terlipressin (diacetate). This product is intended for research and analytical applications. Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-P4994

Val9-Oxytocin	Vasopressin Receptor	Cardiovascular Disease
Val9-Oxytocin is a full antagonist of **vasopressin (V_1a) receptor**. Val9-Oxytocin is an analog of Oxytocin (HY-17571A) in which changing Gly9 to Val9 .

HY-17572R

Atosiban (Standard) RW22164 (Standard); RWJ22164 (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (Standard) is the analytical standard of Atosiban. This product is intended for research and analytical applications. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-17572AR

Atosiban acetate (Standard) RW22164 acetate (Standard); RWJ22164 acetate (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (acetate) (Standard) is the analytical standard of Atosiban (acetate). This product is intended for research and analytical applications. Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-105239R

Selepressin (Standard) FE 202158 (Standard)	Reference Standards Vasopressin Receptor	Cardiovascular Disease
Selepressin (Standard) is the analytical standard of Selepressin (HY-105239). This product is intended for research and analytical applications. Selepressin (FE 202158) is a selective vasopressin V1A receptor agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1811

Vasopressin 5+ Cited Publications Arginine Vasopressin; Antidiuretic hormone	Structural Classification Neurological Disease Classification of Application Fields Cyclopeptides Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P0004

Lysipressin 2 Publications Verification Lysine Vasopressin; [Lys8]-Vasopressin	Monophenols Animals Classification of Application Fields Other Diseases Phenols Disease Research Fields Source Classification	Adenylate Cyclase Oxytocin Receptor
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-B1811R

Vasopressin (Standard) Arginine Vasopressin (Standard); Antidiuretic hormone (Standard)	Structural Classification Cyclopeptides Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Vasopressin (Standard) is the analytical standard of Vasopressin. This product is intended for research and analytical applications. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

Species:	Human (3)
Tag:	His (2) Strep (1) Tag Free (1)
Source:	Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702070

	CUL5 Protein, Human (sf9) CUL5; Cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing Receptor 1; VACM-1	Human	Sf9 insect cells
	The CUL5 protein is a core component of the SCF-like ECS E3 ubiquitin-protein ligase complex. CUL5 Protein, Human (sf9) is the recombinant human-derived CUL5 protein, expressed by sf9 insect cells , with tag free.

HY-P702071

	CUL5 Protein, Human (sf9, His, StrepⅡ) CUL5; Cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing Receptor 1; VACM-1	Human	Sf9 insect cells
	The CUL5 protein is a core component of the SCF-like ECS E3 ubiquitin-protein ligase complex. CUL5 Protein, Human (sf9, His, Strep) is the recombinant human-derived CUL5 protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.

HY-P790108

	NLRP3 Protein, Human (His) Angiotensin/Vasopressin Receptor AII/AVP-like; Caterpiller protein 1.1; Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; NLRP3; NALP3; PYPAF1; CIAS1	Human	E. coli
	The NLRP3 protein acts as a sensor in the NLRP3 inflammasome, which is activated in response to membrane defects. It forms a complex with CASP1 and PYCARD/ASC, promotes the release of IL1B, IL18 and GSDMD, and induces pyroptosis. NLRP3 Protein, Human (His) is the recombinant human-derived NLRP3, expressed by E. coli, with C-6*His labeled tag.

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HY-B1811AS1

Vasopressin-d5 TFA

Vasopressin-d5 TFA is the TFA salt form of Vasopressin-d5 (HY-B1811S1). Vasopressin-d5 TFA is an isotope-labeled compound of Vasopressin (HY-B1811). Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-B1811S1

Vasopressin-d5

Vasopressin-d5 is anIsotope-labeled compound of Vasopressin. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-18346S

Mozavaptan-d6

Mozavaptan-d6 (OPC-31260-d6) is the deuterium labeled Mozavaptan. Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V₂ receptor antagonist with an IC₅₀ of 14 nM. Mozavaptan shows ~85-fold selectivity for V₂ receptor over V₁ receptor (IC₅₀ of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment .

HY-17000S

Tolvaptan-d7
Tolvaptan-d₇ is the deuterium labeled Tolvaptan. Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC₅₀ of 1.28μM for the inhibition of AVP-induced platelet aggregation .

HY-17572S

Atosiban-d5 TFA
Atosiban-d₅ TFA (RW22164-d₅ TFA) is the deuterium labeled Atosiban TFA. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive **vasopressin/oxytocin receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (2) IP (1) WB (2) ELISA (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

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HY-P810728

	NLRP3 Antibody (YA9972) C1orf7, CIAS1, NALP3, PYPAF1, NLRP3, Angiotensin/Vasopressin Receptor AII/AVP-like, Caterpiller protein 1.1, Cold-induced autoinflammatory syndrome 1 protein, Cryopyrin, PYRIN-containing APAF1-like protein 1, CLR1.1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	NLRP3 Antibody (YA9972) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to NLRP3 Antibody.

HY-P86650

	NLRP3 Antibody (YA6342) NLRP3; C1orf7; CIAS1; NALP3; PYPAF1; NACHT, LRR and PYD domains-containing protein 3; Angiotensin/Vasopressin Receptor AII/AVP-like; Caterpiller protein 1.1CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	NLRP3 Antibody (YA6342) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NLRP3.

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