1 Result for "

YDH704

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YDH704" in MCE Product Catalog:

Cat. No.: HY-187370
Target:  

HDAC PAK PD-1/PD-L1

Research Areas:  

Cancer

YDH-704 is a PAK1/HDAC10 inhibitor, with IC50 values of 0.05 μM and 0.02 μM against human targets, respectively. YDH-704 blocks PAK1-mediated oncogenic signaling pathways, inhibits the proliferation and migration of tumor cells, suppresses the epigenetic regulatory function of HDAC10, downregulates PD-L1 expression, and regulates polyamine metabolism. YDH-704 reduces MDSC/Treg infiltration, enhances the infiltration and activation of CD8 + T cells, and inhibits tumor growth and lung metastasis. YDH-704 can be used for research on triple-negative breast cancer .
loading...
    loading...