6 Results for "

acute airway inflammation

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "acute airway inflammation" in MCE Product Catalog:

Cat. No.: HY-P990094
CAS No.: 2643974-98-3
Synonyms: CSL311

Target:  

c-Fms

Research Areas:  

Inflammation/Immunology

Trabikibart (CSL311) is a specific inhibitor targeting the βc receptor (CSF2RB) that inhibits signal transduction mediated by GM-CSF, IL-5, and IL-3. Trabikibart exhibits significant anti-inflammatory and anti-edema effects, reduces myeloid cell infiltration, and inhibits inflammatory cell survival. Trabikibart also possesses antiviral immune functions, which alleviate pulmonary inflammation, reverse airway dysfunction and fibrosis, and thereby restore impaired pulmonary function. Trabikibart can be used in research on related diseases such as acute respiratory distress syndrome, viral pneumonia, asthma, and chronic rhinosinusitis with nasal polyps .
loading...
    loading...
Cat. No.: HY-145310
CAS No.: 2230496-99-6
Purity:  99.86%
Research Areas:  

Inflammation/Immunology

ZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities. ZL0590 can reduce mucosal inflammation in animal models of inflammatory bowel disease and restores tissue architecture. ZL0590 can be used in research on inflammatory diseases such as inflammatory bowel disease .
loading...
    loading...
Cat. No.: HY-169138
CAS No.: 140841-32-3
Target:  

Lipoxygenase

Research Areas:  

Inflammation/Immunology

ZD 2138 is a selective 5-lipoxygenase (5-lipoxygenase) inhibitor with an IC50 of 20-50 nM. ZD 2138 inhibits cytokine-induced rolling and adhesion of leukocytes on bovine aortic endothelial cells. ZD 2138 is applicable to research related to inflammatory diseases such as acute asthma .
loading...
    loading...
Cat. No.: HY-125495
CAS No.: 122946-43-4
Target:  

NO Synthase

Research Areas:  

Inflammation/Immunology

Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease .
loading...
    loading...
Cat. No.: HY-174604
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL4 mRNA encodes the human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4 mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation.
loading...
    loading...
Cat. No.: HY-P10854
CAS No.: 2415370-74-8
TAT-N15 is a p55PIK inhibitor with remarkable anti-inflammatory activity and neuroprotective effects. TAT-N15 can significantly inhibit the activation of IL-6, IL-8, Akt, and NF-κB pathways, as well as suppress the protein expression of phosphorylated STAT3 and NF-κB. By inhibiting the activation of Akt, STAT3, and NF-κB pathways, TAT-N15 is used in research on acute conjunctivitis, allergic rhinitis, chronic obstructive pulmonary disease (COPD), and stroke .
loading...
    loading...