11 Results for "

amide bond cleavage

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "amide bond cleavage" in MCE Product Catalog:

Cat. No.: HY-P1883A
Target:  

Fluorescent Dye

Research Areas:  

Infection

Bacterial Sortase Substrate III, Abz/DNP TFA is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP TFA undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .
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Cat. No.: HY-P5481
CAS No.: 1807943-24-3
Target:  

Inhibitory Antibodies

Research Areas:  

Others

DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)
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Cat. No.: HY-P2498A
Target:  

Cathepsin

Research Areas:  

Cancer

Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .
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Cat. No.: HY-P4332
CAS No.: 113866-16-3
Research Areas:  

Cardiovascular Disease

Boc-Glu(OBzl)-Ala-Arg-AMC is a fluorogenic substrate for coagulation factor XIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .
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Cat. No.: HY-P2498
CAS No.: 839730-93-7
Target:  

Cathepsin

Research Areas:  

Others

Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .
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Cat. No.: HY-P1883
CAS No.: 2857862-12-3
Target:  

Fluorescent Dye

Research Areas:  

Infection

Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .
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Cat. No.: HY-P11325
Research Areas:  

Others

Ac-RR-AFC TFA is a Cathepsin B fluorogenic substrate (Ex=400 nm, Em=505 nm). Cathepsin B activity in cells lysates is determined by measuring cleavage of Ac-RR-AFC TFA and its cleavage occurs at the RR-AFC amide bond. Ac-RR-AFC TFA can be used for activity assays and mechanistic studies on cathepsin B .
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Cat. No.: HY-P4333
CAS No.: 73554-94-6
Target:  

Fluorescent Dye

Research Areas:  

Cardiovascular Disease

Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate for factors IXa and XIIa. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .
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Cat. No.: HY-155070
Research Areas:  

Cancer

SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer .
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Cat. No.: HY-186231
CAS No.: 194228-49-4
Target:  

Others

Research Areas:  

Others

Tetraphenyl (p-O-C6-Br) porphyrin is a brominated porphyrin derivative and catalyst. Tetraphenyl (p-O-C6-Br) porphyrin catalyzes the cleavage of amide bonds and ester bonds in specific substrates. Tetraphenyl (p-O-C6-Br) porphyrin is applicable to research in the field of palladium catalysis .
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Cat. No.: HY-117641
CAS No.: 121584-61-0
Target:  

Ser/Thr Protease

Research Areas:  

Cardiovascular Disease

CP 81282 is a tripeptide aspartic protease inhibitor, with an IC50 of 1 nM against human renin and an IC50 of 11 nM against endopeptidase. CP 81282 is applicable to the research of hypertension .
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