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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
angiogenic diseases
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "angiogenic diseases" in MCE Product Catalog:
13
13 Publications Verification
Cat. No.: HY-117661
CAS No.: 1818389-84-2
Research Areas:
SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease .
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2 Cited Publications
Cat. No.: HY-N5077
CAS No.: 18696-26-9
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Cruciferae Phenols Plants Disease Research Fields Inflammation/Immunology
Target:
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Category:
Alkaloids Monophenols Other Alkaloids Cruciferae Phenols Plants Disease Research Fields Cancer
Target:
1
1
1 Cited Publications
Cat. No.: HY-13545
CAS No.: 251579-55-2
Target:
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
Synonyms: AR-13324 M1 metabolite
Research Areas:
AR-13503 (AR-13324 M1 metabolite) is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research .
Synonyms: CR6086
Research Areas:
Vorbipiprant (CR6086) is an orally active EP4 receptor antagonist with high selectivity for the human EP4 receptor (Ki: 16.6 nM). Vorbipiprant has immunomodulatory, anti-inflammatory, antitumor, and anti-angiogenic activities. Vorbipiprant can inhibit the expression of multiple pro-inflammatory cytokines and the activation of immune cells, and convert "cold" tumors unresponsive to immune checkpoint inhibitors into "hot" tumors. Vorbipiprant is used in the research of diseases such as rheumatoid arthritis and colon cancer .
Cat. No.: HY-P3369
CAS No.: 2417491-82-6
Synonyms: AXT-107
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Target:
Cat. No.: HY-P1615
CAS No.: 1006388-38-0
Synonyms: UPARANT
Cat. No.: HY-P5840
CAS No.: 1206475-79-7
Target:
Research Areas:
Cat. No.: HY-15893G
CAS No.: 89464-63-1
Synonyms: Dimethyloxallyl Glycine (GMP)
Cat. No.: HY-N2911
CAS No.: 60297-37-2
Target:
VEGFR Ferroptosis PI3K Akt mTOR Cannabinoid Receptor p38 MAPK
Research Areas:
Auriculasin is an anticancer agent that inhibits VEGFR2, PI3K/AKT/mTOR, MAPK. Auriculasin can inhibit cell proliferation, induce cell apoptosis, and inhibit angiogenesis, and promotes mitochondrial oxidative stress and ferroptosis. Auriculasin is also active at the cannabinoid receptor CB1 with an IC50 of 8.92 μM. Auriculasin can be used in cancer research, especially related diseases such as prostate cancer and non-small cell lung cancer, as well as research on the development of anti-angiogenic drugs .
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Research Areas:
Anecortave acetate is a potent ocular angiostatic agent. Anecortave acetate inhibits neovascularization which is induced by many different angiogenic factors, and increases plasminogen activator inhibitor-1 (PAI-1) mRNA expression. Anecortave acetate can be used to research ocular neovascular diseases .
Cat. No.: HY-P3395
CAS No.: 197151-46-5
Synonyms: Human chromogranin A 352–372
Target:
Research Areas:
Cat. No.: HY-N5077R
CAS No.: 18696-26-9
Category:
Alkaloids Monophenols Other Alkaloids Cruciferae Phenols Plants
Cat. No.: HY-N2518R
CAS No.: 11027-63-7
Synonyms: Agnoside (Standard)
Category:
other families Monophenols Iridoids Terpenoids Phenols Plants
Cat. No.: HY-178919
CAS No.: 2996841-28-0
Research Areas:
N-19004 is a FPR1 antagonist. N-19004 shows broad-spectrum antibacterial effects against a variety of pathogens. N-19004 exhibits significant retinal protective effects in the rd10 mouse model of retinitis pigmentosa (RP). N-19004 can attenuate retinal dysfunction, mitigate rod and cone degeneration, and reduce immune cell activation, gliosis, inflammation, oxidative stress, and apoptosis. N-19004 can reduce the size of laser-induced choroidal lesions and promote edema absorption through dual anti-inflammatory and anti-angiogenic effects. N-19004 can be used for the research of retinal degenerative diseases such as retinitis pigmentosa .
Cat. No.: HY-121638B
CAS No.: 861123-84-4
Target:
Research Areas:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
(E/Z)-CU-3 is a MCL-1 modulator. (E/Z)-CU-3 can be used to study hyperproliferative diseases, angiogenic diseases, cell cycle regulation diseases, autophagy regulation diseases, inflammatory diseases and/or infectious diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
