7 Results for "

angiotensin-(1-7)

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "angiotensin-(1-7)" in MCE Product Catalog:

18
Talfirastide
Talfirastide
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18 Cited Publications
Cat. No.: HY-12403
CAS No.: 51833-78-4
Purity:  99.75%
Synonyms: TXA127; angiotensin (1-7); Ang-(1-7)
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Angiotensin Receptor Angiotensin-converting Enzyme (ACE)

Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .
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18
Talfirastide acetate
Talfirastide acetate
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18 Cited Publications
Cat. No.: HY-12403A
CAS No.: 2855063-75-9
Purity:  99.87%
Synonyms: TXA127 acetate; angiotensin (1-7) acetate; Ang-(1-7) acetate
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Endocrinology

Target:  

Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite

Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .
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17
AVE 0991
AVE 0991
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17 Cited Publications
Cat. No.: HY-15778
CAS No.: 304462-19-9
Purity:  98.88%
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease Endocrinology

AVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM .
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1
(D-Pro7)-Angiotensin I/II (1-7)
(D-Pro7)-Angiotensin I/II (1-7)
0 Images
1 Cited Publications
Cat. No.: HY-P1656
CAS No.: 586962-44-9
Target:  

Angiotensin Receptor Mas-related G-protein-coupled Receptor (MRGPR)

Research Areas:  

Cardiovascular Disease

(D-Pro7)-Angiotensin I/II (1-7) is a potent Mas receptor inhibitor with a Ki of 0.001 μM for rat receptors. (D-Pro7)-Angiotensin I/II (1-7) competitively blocks the binding of Angiotensin-(1-7) to the Mas receptor and attenuates the vasodilatory effect of rat aortas under physiological and hypertensive conditions. (D-Pro7)-Angiotensin I/II (1-7) can be used for studies on the function of the renin-angiotensin system and the pathological mechanisms of hypertension .
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Talfirastide (Standard)
Talfirastide (Standard)
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Cat. No.: HY-12403R
CAS No.: 51833-78-4
Synonyms: TXA127 (Standard); angiotensin (1-7) (Standard); Ang-(1-7) (Standard)
Category:  

Natural Products Endogenous metabolite

Target:  

Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite Reference Standards

Talfirastide (Standard) is the analytical standard of Talfirastide. This product is intended for research and analytical applications. Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .
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A-779 TFA
A-779 TFA
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Cat. No.: HY-P0216A
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

A-779 TFA is a selective angiotensin-(1-7) (Ang-(1-7)) antagonist. A-779 TFA blocks Arachidonic acid release, bradykinin potentiation effects and hypotensive action. A-779 TFA exerts diuretic effects in non-pregnant rats, antidiuretic effects in late-pregnant rats, and also inhibits feed intake and water consumption in late-pregnant rats. A-779 TFA attenuates the regulatory effects of prostacyclin, nitric oxide and thromboxane A2 associated with angiotensin-(1-7). A-779 TFA can be used in studies related to hypertension .
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PNA5
PNA5
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Cat. No.: HY-167153
CAS No.: 2186644-51-7
Target:  

Interleukin Related Reactive Oxygen Species (ROS)

Research Areas:  

Cardiovascular Disease Neurological Disease Inflammation/Immunology

PNA5 is a novel, blood-brain barrier permeable glycosylated angiotensin-(1-7) peptide and MasR agonist. PNA5 inhibits IL-7, increases IL-10. PNA5 inhibits ROS generation, decreases Iba-1 expression. PNA5 exhibits sustained cognitive protective effects. PNA5 rescues blunted cerebral functional hyperemia. PNA5 can be used in the research of inflammation-related brain diseases .
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