Search Result

Results for "

antibacterial peptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (3) Aminopeptidase (3) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (40) Apoptosis (13) Bacterial (183) Beta-lactamase (1) Biochemical Assay Reagents (2) Caspase (2) CMV (3) COX (1) Cytochrome P450 (2) Dengue Virus (2) DNA/RNA Synthesis (3) Drug Intermediate (3) Endogenous Metabolite (3) Enterovirus (2) Environmental Pollutants (2) ERK (1) Fluorescent Dye (1) Fungal (19) Glycosidase (1) HBV (1) HCV (1) HIV (6) HPV (1) HSV (4) Influenza Virus (3) Interleukin Related (6) Mitochondrial Metabolism (3) MMP (2) MOFs (1) Na+/K+ ATPase (1) NADH Dehydrogenase (1) NF-κB (3) NO Synthase (2) NOD-like Receptor (NLR) (2) p38 MAPK (1) Parasite (6) Platelet-activating Factor Receptor (PAFR) (1) Proteasome (4) Reactive Oxygen Species (ROS) (4) Reference Standards (4) TNF Receptor (6) Toll-like Receptor (TLR) (1) Topoisomerase (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (4) Infection (187) Inflammation/Immunology (26) Metabolic Disease (3) Neurological Disease (3)
Oligonucleotides:	Polymers (1)

199

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

160

Peptides

Natural
Products

Oligonucleotides

Targets Recommended: RXFP Receptor Formyl Peptide Receptor (FPR) Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) Connective Peptide CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4855

CRAMP (mouse) 1 Publications Verification	Bacterial TNF Receptor	Infection Inflammation/Immunology
CRAMP (mouse) is an antibacterial peptide and a functional homolog of LL-37 . CRAMP (mouse) exhibits potent antibacterial activity against Gram-negative bacteria . The complex formed by CRAMP (mouse) and CpG can activate macrophages to secrete TNF-α . CRAMP (mouse) plays a key role in wound healing, immune regulation and maintenance of intestinal homeostasis .

HY-P5712

Gramicidin S 1 Publications Verification Gramicidin soviet	Antibiotic Bacterial Na+/K+ ATPase	Infection
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC₅₀s of 41 μM, 24 μM, and 3 μM for Na ⁺/K ⁺-ATPase, tobacco leaf plasma membrane Mg ²⁺/K ⁺-ATPase, and rat heart plasma membrane Ca ²⁺-ATPase, respectively .

HY-W007056

Fmoc-N-me-Trp(Boc)-OH	Amino Acid Derivatives Biochemical Assay Reagents Drug Intermediate	Infection
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .

HY-W074648

Antibacterial agent 18	MOFs Bacterial	Infection
Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .

HY-P3328A

MDP1 acetate	Bacterial	Infection
MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .

HY-W142073

7-Methyl-DL-tryptophan 7-Methyltryptophan	Amino Acid Derivatives	Infection
7-Methyl-DL-tryptophan (7-Methyltryptophan) is an amino acid derivative, which is a key precursor for biosynthesis of many non-ribosomal peptide antibiotics. 7-Methyl-DL-tryptophan plays an important role in synthesis of high-efficiency antibacterial agents and analogues thereof .

HY-P5714

Abaecin	Bacterial	Infection
Abaecin is an antibacterial response peptide. Abaecin shows specific activity against an Apidaecin-resistant Xanthomonas strain .

HY-W019032

Fmoc-D-Dab(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .

HY-P1350

H-Lys-Trp-Lys-OH	Bacterial	Infection
H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.

HY-P2317

Cecropin P1, porcine	Bacterial Endogenous Metabolite	Infection
Cecropin P1, porcine is an *antibacterial* peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection .

HY-P5710

LCI peptide	Bacterial	Infection
LCI peptide is an antimicrobial peptide with antibacterial activity. LCI peptide is active against plant pathogens, Xanthomonas and Pseudomonas, including E. coli, Gentamicin-resistant MRSA and Xoo .

HY-P11080

Oncocin	Bacterial	Infection
Oncocin is an *antibacterial* peptide. It belongs to proline-rich antimicrobial peptides (PrAMPs). Oncocin works against Gram-negative bacteria. It has MIC values of 0.125-8 μg/mL for 34 strains and clinical isolates of Enterobacteriaceae and nonfermenters. Oncocin binds to the substrate-binding domain of the chaperone DnaK. The binding has dissociation constants in the micromolar range. This binding causes protein misfolding and aggregation and the bacteria death .

HY-P11189

Astacidin 1	Bacterial	Infection
Astacidin 1 is an *antibacterial* peptide. Astacidin 1 can be produced by a proteolytic cleavage from hemocyanin under acidic conditions. Astacidin 1 has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria .

HY-P3459

Tet-213	Bacterial	Infection
Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair .

HY-P3459A

Tet-213 TFA 1 Publications Verification	Bacterial	Infection
Tet-213 TFA is a antimicrobial peptide. Tet-213 TFA has broad spectrum antibacterial activity. Tet-213 TFA can promote infected wound repair .

HY-P5548

CaLL	Bacterial	Infection Cancer
CaLL is an antimicrobial peptide. CaLL has antibacterial activity against B. anthracis, B. anthracis (vegetative), and B. cepacia (MIC: 7.8, 31.3, 31.3 μg/mL) .

HY-P5572

Aurein 2.5	Antibiotic Fungal Bacterial	Infection
Aurein 2.5 is an antibiotic antimicrobial peptide. Aurein 2.5 has antibacterial and antifungal activity

HY-P11093

Papiliocin	Antibiotic Bacterial Fungal Apoptosis Reactive Oxygen Species (ROS) TNF Receptor NO Synthase Interleukin Related NF-κB Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Papiliocin is a potent peptide antibiotic with both anti-inflammatory and antibacterial activities. Papiliocin is primarily active against Gram-negative *bacteria. Papiliocin exhibits strong anti-inflammatory activity against cell, exerting its anti-inflammatory activity by inhibiting the production of NO and the secretion of TNF-α* and MIP-2. Papiliocin participates in the innate defense response mechanism by inhibiting the Toll-like receptor pathway and NF-κB. Papiliocin induces apoptosis in fungal cells and increases the total level of intracellular ROS. Papiliocin acts as an effective antiseptic peptide in sepsis models. Papiliocin is useful in anti-inflammatory and antibacterial research .

HY-P5702

EP3	Bacterial Apoptosis Fungal	Infection
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-P1063

LF11	Bacterial Antibiotic	Infection
LF11 is a peptide with *antibacterial* activity .

HY-P1063A

LF11 TFA	Bacterial Antibiotic	Infection
LF11 TFA is a peptide with *antibacterial* activity .

HY-P5719

Andropin	Bacterial	Infection
Andropin is a male-specific antibacterial peptide that can be found in Drosophila melanogaster .

HY-P5720

Peptide 5e	Bacterial	Infection
Peptide 5e is an antimicrobial peptide. Peptide 5e inhibits E. coli, S. aureus, and C. albicans with MIC values of 30, 5, 25 μg/mL respectively .

HY-P5735

Bactenecin 7 Bac-7	Bacterial	Infection
Bactenecin 7 is an antibacterial peptide active against the growth of Enterobacter cloacae (MICs, 25 to 200μg/ml) .

HY-P5711

NEMURI	Bacterial	Infection
NEMURI is an antimicrobial peptide with sleep-promoting effect .

HY-P5724

Nv-CATH	Bacterial	Infection
Nv-CATH is an *antibacterial* peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality .

HY-113561

Biphenomycin A LL-AF283α	Antibiotic Bacterial	Infection
Biphenomycin A (LL-AF283α) is a cyclic peptide antibiotic that can be found in Streptomyces griseorubiginosus 43708. It has antibacterial activity and can be used in research in the field of anti-infection .

HY-P5704

K11	Bacterial	Infection
K11 is an antimicrobial peptide. K11 is active against MDR/XDR K. pneumoniae isolates (MIC: 8-512 μg/mL), and inhibits bacterial biofilm formation. K11 can act synergistically with antibiotics (Chloramphenicol (HY-B0239), Meropenem (HY-13678), Rifampicin (HY-B0272), etc.) against drug-resistant K. pneumoniae. K11 has high thermal and wide pH stability .

HY-P5565

RP-1	Bacterial	Infection Cancer
RP-1 is an antimicrobial peptide, and is active against S. aureus, S. typhimurium, E. coli, and C. albicans .

HY-P10200

CP7-FP13-2	Bacterial	Infection
CP7-FP13-2 is a peptide with antivirulence factor and *antibacterial* activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice .

HY-P5734

Bactenecin 5	Bacterial	Infection
Bactenecin 5 is a bovine antibacterial peptide. Bactenecin 5 is active against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. T, with MIC values of 12-25 μg/mL .

HY-P5689

Maximin 42	Bacterial	Infection
Maximin 42 is an antimicrobial peptide. Maximin 42 has antibacterial activity against S. aureus (MIC: 37.5 μg/mL). Maximin 42 has hemolytic activities against human red cells .

HY-P5692

Maximin 77	Bacterial	Infection
Maximin 77 is an antimicrobial peptide. Maximin 77 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 77 has hemolytic activities against human red cells .

HY-P5691

P1	Bacterial	Infection Cancer
P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .

HY-P5687

Im5	Bacterial	Infection
Im5, an antimicrobial peptide, has antibacterial (MIC: 10, 2.5-5, 0.5-1 μM for E. coli, S. aureus, B. subtilis respectively) and hemolytic activity (EC₅₀: 28 μM) .

HY-P5696

Xenopsin precursor fragment	Bacterial Parasite Fungal	Infection
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .

HY-P5682

Maximin 41	Bacterial	Infection
Maximin 41 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus (MIC: 75 μg/mL). Maximin 41 has hemolytic activities against human red cells .

HY-P5690

Distinctin	Bacterial	Infection
Distinctin is an antimicrobial peptide. Distinctin can be isolated from frog skin. Distinctin has antibacterial activity against E. faecalis, P. aeruginosa, S. aureus and E. coli (MIC: 14.5, 28.0, 28.0, 14.5 μM) .

HY-P5701

EP2	Bacterial Fungal	Infection
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-P5685

Maximin 49	Bacterial	Infection
Maximin 49 is an antimicrobial peptide. Maximin 49 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 49 has hemolytic activities against human and rabbit red cells .

HY-P5603

Bovine neutrophil beta-defensin 12 BNBD-12	Bacterial	Infection
Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has *antibacterial* activity against Escherichia coli and Staphylococcus aureus .

HY-P5695

GP-2B	Bacterial	Infection
GP-2B is an antimicrobial peptide. GP-2B shows antibacterial activity against Gram-positive strain (MIC: 8-128 μg/mL for S. aureus and Enterococcus faecalis) .

HY-W714002

Feglymycin	HIV Bacterial	Infection
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus) .

HY-P5688

Maximin 68	Bacterial	Infection
Maximin 68 is an antimicrobial peptide. Maximin 68 has antibacterial activity against C. albicans, S. aureus, E. coli, B. subtilis (MIC: 18.8, 9.4, 37.5, 9.4 μg/mL). Maximin 68 has hemolytic activities against human and rabbit red cells .

HY-P5683

Maximin 45	Bacterial	Infection
Maximin 45 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus, E. coli, B. subtilis (MIC: 4.7, 9.4, 75 μg/mL). Maximin 45 has hemolytic activities against human and rabbit red cells .

HY-P5686

Maximin 78	Bacterial	Infection
Maximin 78 is an antimicrobial peptide. Maximin 78 has antibacterial activity against C. albicans, S. aureus, B. subtilis (MIC: 37.5, 4.7, 37.5 μg/mL). Maximin 78 has hemolytic activities against human and rabbit red cells .

HY-P5684

Maximin H39	Bacterial	Infection
Maximin H39 is an antimicrobial peptide. MaximinH39 has antibacterial activity against C. albicans, S. aureus, B. subtilis (MIC: 9.4, 9.4, 18.8 μg/mL). Maximin H39 has hemolytic activities against human and rabbit red cells .

HY-P11161

Fowlicidin-2	Bacterial TNF Receptor	Infection Inflammation/Immunology
Fowlicidin-2 is an alpha helical *antibacterial* peptide. Fowlicidin-2 can significantly inhibit the production of TNF-α and NO. Fowlicidin-2 can be used in the study of infectious conditions and sepsis .

HY-P11163

Eumenitin	Bacterial Glycosidase	Infection
Eumenitin is an antibacterial peptide with strong membrane activity, broad-spectrum *antibacterial* activity, and almost no hemolytic toxicity. Eumenitin has inhibitory effects on various Gram positive and Gram negative bacteria. Eumenitin can induce the release of β-hexosaminidase from rat peritoneal mast cells and RBL-2H3 cells. Eumenitin can be used in the research of infectious conditions .

HY-P10970

RT2	Bacterial	Infection
RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide, with main targets including lipopolysaccharide (LPS) on the bacterial surface and intracellular DNA. RT2 binds to bacterial surface LPS, and interacts with cytoplasmic membrane phospholipids, enabling it to rapidly penetrate the bacterial cell membrane and enter the cell, and then bind to components such as DNA in the cytoplasmic membrane, thereby exerting antibacterial effects. RT2 is promising for research of acute and chronic infections caused by planktonic bacteria .

Cat. No.	Product Name

HY-L110

Cyclic Peptide Library

97 compounds

Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs.

MCE offers a unique collection of 97 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.

Cat. No.	Product Name	Type

HY-W250308

ε-Poly-L-lysine (MW 3800-4200)

Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)

Biochemical Assay Reagents

Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .

HY-126437A

Poly-L-lysine hydrochloride

1 Publications Verification

Biochemical Assay Reagents

Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .

Cat. No.	Product Name		Classification

HY-126437A

Poly-L-lysine hydrochloride 1 Publications Verification		Polymers
Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

antibacterial peptide

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

NaturalProducts

Oligonucleotides

Natural
Products