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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
antibody Fc glycan
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "antibody Fc glycan" in MCE Product Catalog:
Cat. No.: HY-E70132
CAS No.: 37278-88-9
Synonyms: Endo D
Target:
Research Areas:
Endo-β-N-acetylglucosaminidase D (Endo D), isolated from Streptococcus pneumoniae. Endo-β-N-acetylglucosaminidase D hydrolyzes Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-β-N-acetylglucosaminidase D possesses transglycosylation activity with sugar oxazoline as the donor substrate .
Cat. No.: HY-164169
CAS No.: 912921-33-6
Research Areas:
GDP-azido-fucose is a glycoengineering tool. GDP-azido-fucose modifies complex glycans by adding an azido-fucose group. GDP-azido-fucose can install azido-fucose tags on antibody Fc glycans for site-specific payload conjugation, thereby forming antibody-drug conjugates with defined ratios .
Cat. No.: HY-156230
CAS No.: 2855124-74-0
Target:
Research Areas:
Man-GIcNAc-oxazoline is a disaccharide oxazoline based on Manβ1,4GlcNAc. Man-GIcNAc-oxazoline serves as a donor substrate for transglycosylation in endoglycosidase-mediated antibody Fc glycan remodeling. Man-GIcNAc-oxazoline can be modified with azides, PEG-linked azides, fluorescent probes, biotin groups, ligands or prodrugs. Man-GIcNAc-oxazoline can be used for the synthesis of antibody-drug conjugates (ADC). Man-GIcNAc-oxazoline is applicable for cancer research .
Cat. No.: HY-164169A
CAS No.: 944560-34-3
Research Areas:
GDP-azido-fucose disodium is a glycoengineering tool. GDP-azido-fucose disodium modifies complex glycans by adding an azido-fucose group. GDP-azido-fucose disodium can install azido-fucose tags on antibody Fc glycans for site-specific payload conjugation, thereby forming antibody-drug conjugates with defined ratios .
Cat. No.: HY-156232
CAS No.: 2855124-88-6
Target:
Research Areas:
Gal-GlcNAc-oxazoline is an intermediate bearing an azido group, which can be used in studies related to the synthesis of antibody-drug conjugates (ADC) via click chemistry .
Cat. No.: HY-156231
CAS No.: 2855124-81-9
Target:
Research Areas:
Glc-GlcNAc-oxazoline is a disaccharide intermediate that can introduce an azide side chain onto the sugar moiety. Glc-GlcNAc-oxazoline can be used in studies related to the synthesis of antibody-drug conjugates (ADC) via click chemistry .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
