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anticoagulant agent

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46

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15

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1

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0682
    Ethylenediaminetetraacetic acid
    Maximum Cited Publications
    29 Publications Verification

    EDTA

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid
  • HY-116282
    Dextran sulfate sodium salt (MW 5000)
    5 Publications Verification

    DSS (MW 5000); DXS (MW 5000)

    		 HIV Complement System Apoptosis Infection Inflammation/Immunology
    Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
    Dextran sulfate sodium salt (MW 5000)
  • HY-112624P
    Dextran T500 (MW 500,000)
    1 Publications Verification

    Dextran 500; Dextran D500; Dextran T500(MW 440000-560000)

    		 Biochemical Assay Reagents Others
    Dextran T500 MW 500,000 (Dextran 500; Dextran D500; Dextran T500 MW 440000-560000) is a polymer of anhydroglucose with the average molecular weight of 500,000. Dextran T500 MW 500,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
    Dextran T500 (MW 500,000)
  • HY-107911
    Protamine sulfate
    3 Publications Verification

    		 Thrombin Metabolic Disease
    Protamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer .
    Protamine sulfate
  • HY-Y0682A
    Ethylenediaminetetraacetic acid disodium dihydrate
    20+ Cited Publications

    EDTA disodium dihydrate

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid disodium dihydrate
  • HY-10274
    Dabigatran etexilate
    4 Publications Verification

    BIBR 1048

    		 Thrombin Cardiovascular Disease
    Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
    Dabigatran etexilate
  • HY-116282A
    Dextran sulfate sodium salt (MW 4500-5500)

    DSS (MW 4500-5500); DXS (MW 4500-5500)

    		 HIV Apoptosis Complement System Infection Inflammation/Immunology
    Dextran sulfate sodium salt (DSS) (MW 4500-5500) is a polymer of dehydrated glucose with a molecular weight of approximately 4500-5500. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 4500-5500) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 4500-5500) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (MW 4500-5500) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 4500-5500) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
    Dextran sulfate sodium salt (MW 4500-5500)
  • HY-B1009
    Ethylenediaminetetraacetic acid trisodium salt
    25+ Cited Publications

    EDTA trisodium salt; Trisodium EDTA

    		 Environmental Pollutants Bacterial SOD Ferroptosis Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid trisodium salt
  • HY-10787
    Ximelagatran
    1 Publications Verification

    H 376/95

    		 Thrombin Cardiovascular Disease
    Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics .
    Ximelagatran
  • HY-112624D
    Dextran T60 (MW 60,000)

    Dextran 60; Dextran D60; Dextran T60(MW 54000-66000)

    		 Biochemical Assay Reagents Others
    Dextran T60 MW 60,000 (Dextran 60; Dextran D60; Dextran T60 MW 54000-66000) is a polymer of anhydroglucose with the average molecular weight of 60,000. Dextran T60 MW 60,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
    Dextran T60 (MW 60,000)
  • HY-122542B
    PPACK TFA
    2 Publications Verification

    		 Ligands for E3 Ligase Molecular Glues IKZF Family Cardiovascular Disease
    PPACK TFA is an orally active, selective molecular glue degrader targeting IKZF2. Through a molecular glue mechanism, PPACK TFA binds to CRBN, recruits IKZF2 to form a ternary complex, and promotes its ubiquitination and proteasomal degradation. This further converts inhibitory regulatory T cells (Treg) into effector-like T cells, enhances CD8 + T cell responses, and modulates the Teff:Treg balance. PPACK TFA also increases the production of the inflammatory cytokine IL-2 and reduces the suppressive activity of Treg. PPACK TFA can be used in cancer immunotherapy research, and exhibits a synergistic effect when combined with immune checkpoint inhibitors such as anti-PD1 .
    PPACK TFA
  • HY-112624Q
    Dextran T800 (MW 800,000)

    Dextran 800; Dextran D800; Dextran T800(MW 750000-850000)

    		 Biochemical Assay Reagents Others
    Dextran T800 MW 800,000 (Dextran 800; Dextran D800; Dextran T800 MW 750000-850000) is a polymer of anhydroglucose with the average molecular weight of 800,000. Dextran T800 MW 800,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
    Dextran T800 (MW 800,000)
  • HY-10274A
    Dabigatran etexilate mesylate
    4 Publications Verification

    BIBR 1048MS; Dabigatran etexilate methanesulfonate

    		 Thrombin Cardiovascular Disease
    Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
    Dabigatran etexilate mesylate
  • HY-W127774
    EDTA hydrate sodium
    20+ Cited Publications

    Ethylenediaminetetraacetic acid hydrate sodium

    		 Biochemical Assay Reagents Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    EDTA (Ethylenediaminetetraacetic acid) hydrate sodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). EDTA hydrate sodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. EDTA hydrate sodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA hydrate sodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
    EDTA hydrate sodium
  • HY-N1745A
    3-Deoxysappanchalcone
    2 Publications Verification

    		 Influenza Virus Infection Inflammation/Immunology Cancer
    3-Deoxysappanchalcone is a kinase inhibitor and antiviral agent. 3-Deoxysappanchalcone directly targets MET, EGFR, AKT, mTOR, p38 MAPK, JNK, thrombin, FXa, and influenza virus neuraminidase, thereby regulating related signaling pathways. 3-Deoxysappanchalcone induces cell cycle arrest, ROS production, and apoptosis. 3-Deoxysappanchalcone exhibits anti-inflammatory, anti-allergic, anticoagulant, and antithrombotic activities. 3-Deoxysappanchalcone is applicable to research related to gefitinib-resistant lung cancer, esophageal squamous cell carcinoma, thrombosis, and influenza virus infection .
    3-Deoxysappanchalcone
  • HY-P2955
    Heparinase II

    		Glycosidase Cancer
    Heparinase II is a glycosidase targeting heparin and heparan sulfate. Heparinase II is promising for research of glycosaminoglycan structure-function analysis, anticoagulant agents and tumor microenvironment modulation .
    Heparinase II
  • HY-P2920
    Protamine from salmon

    		Biochemical Assay Reagents Thrombin Bacterial Infection Cardiovascular Disease
    Protamine from salmon is a biochemical agent with antioxidant, antiheparin and antimicrobial activities. Protamine from salmon neutralizes the anticoagulant effect of heparin, thereby preventing the formation of antithrombin complexes in canine samples pretreated with heparin in vitro .
    Protamine from salmon
  • HY-Y0682B
    Ethylenediaminetetraacetic acid tetrasodium
    20+ Cited Publications

    EDTA tetrasodium

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid tetrasodium
  • HY-18660
    Ciraparantag

    PER977

    		 Factor Xa Thrombin Cardiovascular Disease
    Ciraparantag (PER977) is a thrombin and factor Xa inhibitor. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban .
    Ciraparantag
  • HY-10264S
    Edoxaban-d6

    DU-176-d6

    		 Factor Xa Thrombin Cardiovascular Disease
    Edoxaban-d6 is deuterium labeled Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention. Edoxaban is also a weak inhibitor of thrombin and factor IXaβ (FIXa), with Kis of 6.00 μM and 41.7 μM, respectively, exhibits >10000-fold selectivity for FXa. Edoxaban has antithrombotic properties and has potential for thromboembolic diseases treatment .
    Edoxaban-d6
  • HY-W105700
    Ethylenediaminetetraacetic acid sodium hydrate
    20+ Cited Publications

    EDTA sodium hydrate

    		 Biochemical Assay Reagents Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid sodium hydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid sodium hydrate can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid sodium hydrate
  • HY-W087947
    EDTA dihydrate tripotassium
    20+ Cited Publications

    Ethylenediaminetetraacetic acid dihydrate tripotassium

    		 Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    EDTA dihydrate tripotassium (Ethylenediaminetetraacetic acid dihydrate tripotassium) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). EDTA dihydrate tripotassium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. EDTA dihydrate tripotassium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA dihydrate tripotassium can alleviate the liver fibrosis. EDTA dihydrate tripotassium can be used for coronary artery disease and neural system disease research .
    EDTA dihydrate tripotassium
  • HY-108739
    Idarucizumab

    BI 655075

    		 Thrombin Cardiovascular Disease
    Idarucizumab is a humanized monoclonal antibody fragment. Idarucizumab is first reversal agent for a direct oral anticoagulant (DOAC). Idarucizumab can specifically neutralize the effects of the oral direct thrombin inhibitor in order to restore hemostasis .
    Idarucizumab
  • HY-134685
    Edoxaban impurity 6

    		Factor Xa Thrombin Cardiovascular Disease
    Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention .
    Edoxaban impurity 6
  • HY-134686
    Edoxaban impurity 4

    		Factor Xa Thrombin Cardiovascular Disease
    Edoxaban impurity 4 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention .
    Edoxaban impurity 4
  • HY-W854549
    Heparin pentasaccharide

    Fondaparinux free acid

    		 Factor Xa Cardiovascular Disease
    Heparin pentasaccharide (Fondaparinux) is a chemically synthesized selective factor Xa inhibitor with anticoagulant activity. Heparin pentasaccharide can be utilized in researches related to venous thromboembolic events .
    Heparin pentasaccharide
  • HY-10274R
    Dabigatran etexilate (Standard)

    BIBR 1048 (Standard)

    		 Reference Standards Thrombin Cardiovascular Disease
    Dabigatran etexilate (Standard) is the analytical standard of Dabigatran etexilate. This product is intended for research and analytical applications. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
    Dabigatran etexilate (Standard)
  • HY-B1009R
    Ethylenediaminetetraacetic acid trisodium salt (Standard)

    EDTA trisodium salt (Standard); Trisodium EDTA (Standard)

    		 Ferroptosis Bacterial SOD Reference Standards Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (trisodium salt) (Standard) is the analytical standard of Ethylenediaminetetraacetic acid (trisodium salt). This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid trisodium salt (Standard)
  • HY-Y0682R
    Ethylenediaminetetraacetic acid (Standard)

    EDTA (Standard)

    		 Biochemical Assay Reagents Reference Standards Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (Standard) is the analytical standard of Ethylenediaminetetraacetic acid. This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research [4] .
    Ethylenediaminetetraacetic acid (Standard)
  • HY-Y0682AR
    Ethylenediaminetetraacetic acid disodium dihydrate (Standard)

    EDTA disodium dihydrate (Standard)

    		 Biochemical Assay Reagents Reference Standards Bacterial SOD Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid (disodium dihydrate) (Standard) is the analytical standard of Ethylenediaminetetraacetic acid (disodium dihydrate). This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research [4] .
    Ethylenediaminetetraacetic acid disodium dihydrate (Standard)
  • HY-18660B
    Ciraparantag acetate

    PER977 acetate

    		 Factor Xa Thrombin Cardiovascular Disease
    Ciraparantag (PER977) acetate is a thrombin and factor Xa inhibitor. Ciraparantag acetate is a broad-spectrum reversal agent for anticoagulants, including low molecular weight heparins, unfractionated heparins, and some direct oral anticoagulants, but not VKAs .
    Ciraparantag acetate
  • HY-18660A
    Ciraparantag TFA

    PER977 TFA

    		 Factor Xa Thrombin Cardiovascular Disease
    Ciraparantag (PER977) TFA is a thrombin and factor Xa inhibitor. Ciraparantag TFA is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban .
    Ciraparantag TFA
  • HY-118803
    AS1468240

    		Factor Xa Others
    AS1468240 is an orally active inhibitor for anticoagulant factor Xa (fXa), that inhibits human fXa with IC50 of 8.7 nM. AS1468240 prolongs the coagulation time in mice .
    AS1468240
  • HY-18660S
    Ciraparantag-d8 (tetra(hydrochloride) diacetate)

    PER977-d8 tetrahydrochloride diacetate

    		 Isotope-Labeled Compounds Factor Xa Thrombin Cardiovascular Disease
    Ciraparantag-d8 (PER977-d8) tetrahydrochloride diacetate is the deuterium labeled Ciraparantag (HY-18660). Ciraparantag is a thrombin and factor Xa inhibitor. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban .
    Ciraparantag-d8 (tetra(hydrochloride) diacetate)
  • HY-W127789
    Ethylenediaminetetraacetic acid diammonium

    EDTA diammonium

    		 Biochemical Assay Reagents Others
    Ethylenediaminetetraacetic acid diammonium is a class of organic compounds containing both ammonium and carboxylic acid functional groups. It is commonly used as a chelating agent in various industrial and medical applications, especially in the food and pharmaceutical industries. Ethylenediaminetetraacetic acid diammonium has strong metal ion binding properties and can be used to chelate trace metals that may affect product quality or stability. In addition, it is used as an anticoagulant in blood collection tubes and as a clarifying agent in cosmetic and personal care products.
    Ethylenediaminetetraacetic acid diammonium
  • HY-W127801
    Ethylenediaminetetraacetic acid trisodium hydrate

    EDTA trisodium hydrate

    		 Biochemical Assay Reagents Others
    Ethylenediaminetetraacetic acid (trisodium hydrate) is a class of organic compounds containing carboxylic acid functional groups. It is commonly used as a chelating agent in various industrial and medical applications, especially in the food and pharmaceutical industries. Ethylenediaminetetraacetic acid (trisodium hydrate) has strong metal ion binding properties and can be used to chelate trace metals that may affect product quality or stability. In addition, it is used as an anticoagulant in blood collection tubes and as a stabilizer in some cosmetic and personal care products.
    Ethylenediaminetetraacetic acid trisodium hydrate
  • HY-10274AR
    Dabigatran etexilate mesylate (Standard)

    BIBR 1048MS (Standard); Dabigatran etexilate methanesulfonate (Standard)

    		 Reference Standards Thrombin Cardiovascular Disease
    Dabigatran etexilate (mesylate) (Standard) is the analytical standard of Dabigatran etexilate (mesylate). This product is intended for research and analytical applications. Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
    Dabigatran etexilate mesylate (Standard)
  • HY-W777365
    Ethylenediaminetetraacetic acid-13C4

    EDTA-13C4

    		 Isotope-Labeled Compounds Bacterial SOD Biochemical Assay Reagents Cardiovascular Disease Neurological Disease Cancer
    Ethylenediaminetetraacetic acid- 13C4 (EDTA- 13C4) is the 13C-labeled Ethylenediaminetetraacetic acid (HY-Y0682). Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
    Ethylenediaminetetraacetic acid-13C4
  • HY-N17623
    Ainsliaeasin C

    		Thrombin Cardiovascular Disease
    Ainsliaeasin C, a 7-hydroxycoumarin derivative, is an orally active anticoagulant agent that can be found in Ainsliaea fragrans. Ainsliaeasin C exerts anticoagulant activity both in vitro and in vivo. Ainsliaeasin C can be used for the research on thrombotic disorders .
    Ainsliaeasin C
  • HY-10787R
    Ximelagatran (Standard)

    H 376/95 (Standard)

    		 Reference Standards Thrombin Cardiovascular Disease
    Ximelagatran (Standard) is the analytical standard of Ximelagatran (HY-10787). This product is intended for research and analytical applications. Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcoKinetics and pharmacodynamics .
    Ximelagatran (Standard)
  • HY-180988
    Heparin reversal agent-1

    		Biochemical Assay Reagents Cardiovascular Disease
    Heparin reversal agent-1 (Compound QA-1) is a reversal agent for Heparin (HY-17567). Heparin reversal agent-1 shows neutralization activity. Heparin reversal agent-1 completely reverses the anticoagulant activity of both unfractionated heparin and low-molecular-weight heparins, including Dalte, Enoxa, and Nadro .
    Heparin reversal agent-1
  • HY-N3919
    γ-Methoxyisoeugenol

    		Others Cardiovascular Disease
    γ-Methoxyisoeugenol (Compound 5) is an anticoagulant agent that remarkably prolongs the thrombin time with a good dose-effect relationship at concentrations from 6.25 to 100 mM, but shows no significant differences in prothrombin time .
    γ-Methoxyisoeugenol
  • HY-183649
    BCN-PEG6-OH

    		Biochemical Assay Reagents Cardiovascular Disease
    BCN-PEG6-OH is a neutralizing agent and anticoagulant inhibitor containing strained alkyne. BCN-PEG6-OH undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) click reaction with azido-Warfarin to generate an inactive product that can be rapidly cleared via the kidneys. In mice, BCN-PEG6-OH effectively reduces the anticoagulant activity of azido-Warfarin in a dose-dependent manner, normalizes prothrombin time, and exhibits no inherent anticoagulant or procoagulant effects when administered alone. BCN-PEG6-OH can be used for the research of drug-induced coagulopathy .
    BCN-PEG6-OH
  • HY-N18642
    Soapnut extract

    		Bacterial Infection Inflammation/Immunology
    Soapnut extract is a natural nonionic surfactant that can be used as a skin conditioning agent. It possesses strong detergency, antibacterial, non-polluting, and skin-softening properties. Soapnut extract also exhibits anti-inflammatory, antioxidant, free radical scavenging, and anticoagulant effects.
    Soapnut extract
  • HY-167743
    Platelet aggregation-IN-2

    		Endogenous Metabolite Cardiovascular Disease
    Platelet aggregation-IN-2 is an anti-platelet aggregation agent with significant anticoagulant activity. Platelet aggregation-IN-2 can inhibit platelet aggregation reaction and reduce the risk of thrombosis. The application of Platelet aggregation-IN-2 can potentially be used for the prevention and suppression of cardiovascular diseases .
    Platelet aggregation-IN-2
  • HY-106830
    Pelrinone

    		Phosphodiesterase (PDE) Cardiovascular Disease
    Pelrinone is an orally active cardiotonic agent and PDE III inhibitor with an IC50 of 36 μM. Pelrinone elevates intracellular cAMP levels. The action of Pelrinone is independent of β-adrenergic receptors, and it does not inhibit Na +/K +-ATPase. Pelrinone exerts positive inotropic and vasodilatory effects. Pelrinone inhibits platelet aggregation, reduces thrombus formation, and exerts weak anticoagulant activity without altering hematocrit or circulating platelet counts. Pelrinone can be used in research related to congestive heart failure and coronary thrombosis .
    Pelrinone

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