10424 Results for "

basic chemical raw materials

" in MedChemExpress (MCE) Product Catalog:
Products (10424)

10424 Results for "basic chemical raw materials" in MCE Product Catalog:

159
159 Publications Verification
Cat. No.: HY-13982
CAS No.: 749886-87-1
Purity:  99.30%
Target:  

NF-κB

JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation .
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110
110 Cited Publications
Cat. No.: HY-107455
CAS No.: 1889279-16-6
Purity:  99.87%
A-485, a chemical probe, is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively .
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81
81 Cited Publications
Cat. No.: HY-12071C
CAS No.: 1062368-62-0
Synonyms: DM-3189 hydrochloride
LDN193189 (DM-3189) hydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva .
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80
80 Cited Publications
Cat. No.: HY-B0166C
CAS No.: 5743-28-2
Synonyms: L-Ascorbate calcium dihydrate; Vitamin C calcium dihydrate
L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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78
78 Cited Publications
Cat. No.: HY-17420
CAS No.: 50-18-0
Research Areas:  

Cancer

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.
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78
78 Cited Publications
Cat. No.: HY-17420A
CAS No.: 6055-19-2
Synonyms: Cyclophosphamide monohydrate
Research Areas:  

Cancer

Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
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69
69 Cited Publications
Cat. No.: HY-B0324A
CAS No.: 548-62-9
Synonyms: basic Violet 3; Gentian Violet; Methyl Violet 10B
Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1].
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50
50 Cited Publications
Cat. No.: HY-W250163
CAS No.: 64417-72-7
Synonyms: β-DPN lithium; β-NAD lithium; β-Nicotinamide Adenine Dinucleotide lithium
NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function .
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46
46 Cited Publications
Cat. No.: HY-D1374
CAS No.: 1144107-82-3
Sulfo-Cy5 carboxylic acid potassium is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) .
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45
45 Cited Publications
Cat. No.: HY-19543
CAS No.: 14907-98-3
Synonyms: NSC 172924
Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent . Brusatol increases cellular apoptosis .
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43
43 Cited Publications
Cat. No.: HY-P7004
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; basic Fibroblast Growth Factor; Fibroblast Growth Factor 2 (basic); Fibroblast Growth Factor; Heparin-Binding Growth Factor 2; Prostatropin; HBGF-2; FGF2A; FGF-2; FGF; Fibroblast Growth Factor 2; basic Fibroblast Growth Factor BFGF
Species:  
Source:  
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43
43 Cited Publications
Cat. No.: HY-K0030

MCE Deacetylase Inhibitor Cocktail is a synergistic combination of chemicals designed to preserve the acetylation state of proteins.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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34
34 Cited Publications
Cat. No.: HY-108325A
CAS No.: 96201-88-6
Synonyms: DuP785 sodium; NSC 368390 sodium
Brequinar (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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32
32 Cited Publications
Cat. No.: HY-D0218
CAS No.: 2390-54-7
Synonyms: basic Yellow 1
Thioflavin T is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free); ~450 nm (bound); Emission max.: ~445 nm (free); ~485 nm (bound) .
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32
32 Cited Publications
Cat. No.: HY-13500
CAS No.: 1346704-33-3
Purity:  99.88%
Research Areas:  

Cancer

GSK343, a chemical probe, is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM.
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30
30 Cited Publications
Cat. No.: HY-B1359
CAS No.: 7220-79-3
Synonyms: C.I. basic Blue 9 trihydrate
Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment .
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30
30 Cited Publications
Cat. No.: HY-14536
CAS No.: 61-73-4
Purity:  95.05%
Synonyms: basic Blue 9; CI-52015; Methylthioninium chloride
Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene Blue is a photosensitizer and redox agent. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .
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28
28 Cited Publications
Cat. No.: HY-N1724
CAS No.: 80890-47-7
Synonyms: Antibiotic X 4357B; Folimycin; X 4357B
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
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28
28 Cited Publications
Cat. No.: HY-N1724A
CAS No.: 80890-47-7
Synonyms: Antibiotic X 4357B (purity≥70%); Folimycin (purity≥70%); X 4357B (purity≥70%)
Concanamycin A (purity≥70%) (Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A (purity≥70%) is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
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27
27 Cited Publications
Cat. No.: HY-D0958
CAS No.: 122965-43-9
Synonyms: basic Blue 9 hydrate; CI-52015 hydrate; Methylthioninium chloride hydrate
Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .
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